Laparoscopic vs open distal pancreatectomy for solid pseudopapillary tumor of the pancreas

Table 1 Baseline characteristics of patients undergoing laparoscopic distal pancreatectomy or open distal pancreatectomy for pancreatic solid pseudopapillary tumor n (%)

Characteristics	LDP (n = 15)	ODP (n = 13)	P value
Age (yr)	35.4 ± 13.0	35.2 ± 16.6	0.965
Sex			0.035
Male	0 (0.0)	4 (30.8)
Female	15 (100.0)	9 (69.2)
BMI (kg/m2)	20.8 ± 2.3	22.4 ± 6.1	0.392
Symptoms			0.255
No	10 (66.7)	5 (38.5)
Yes	5 (33.3)	8 (61.5)
Comorbidity	4 (26.7)	4 (30.8)	1.000
ASA score			1.000
1	9 (60.0)	8 (61.5)
2	6 (40.0)	5 (38.5)
Tumor size (cm)	5.1 ± 1.6	7.7 ± 4.1	0.050
Spleen preservation			0.639
No	13 (86.7)	10 (76.9)
Yes	2 (13.3)	3 (23.1)
Combined resection			1.000
Gallbladder	0 (0.0)	1 (7.7)
Gastric stromal tumor	1 (6.7)	0 (0.0)

Data are expressed as n (%) or mean ± SD or unless otherwise specified. BMI: Body mass index; ASA: American Society of Anesthesiologists; LDP: Laparoscopic distal pancreatectomy; ODP: Open distal pancreatectomy.

Table 2 Surgical outcomes of laparoscopic distal pancreatectomy and open distal pancreatectomy for pancreatic solid pseudopapillary tumor n (%)

Outcomes	LDP (n = 15)	ODP (n = 13)	P value
Operating time (min)	171 ± 54	178 ± 75	0.755
EBL (mL)	149 ± 127	580 ± 400	0.002
Transfused patients	1 (6.7)	6 (46.2)	0.029
First flatus time (d)	1.9 ± 0.5	3.5 ± 0.9	0.000
Diet start time (d)	2.3 ± 0.7	4.9 ± 2.1	0.000
Postoperative hospital stay (d)	8.1 ± 1.7	12.8 ± 6.8	0.029
Morbidity	5 (33.3)	5 (38.5)	1.000
Pancreatic fistula	4 (26.7)	4 (30.8)	0.972
Grade A	2 (13.3)	2 (15.4)
Grade B	0 (0.0)	0 (0.0)
Grade C	2 (13.3)	2 (15.4)
Intra-abdominal abscess	1 (6.7)	0 (0.0)	1.000
Pleural effusion	0 (0.0)	1 (7.7)	0.464
Reoperation	0 (0.0)	1 (7.7)	0.464
Percutaneous drainage	2 (13.3)	2 (15.4)	1.000
Mortality	0 (0.0)	0 (0.0)	-

Data are expressed as n (%) or mean ± SD or unless otherwise specified. EBL: Estimated blood loss; LDP: Laparoscopic distal pancreatectomy; ODP: Open distal pancreatectomy.

Table 3 Pathological characteristics of patients undergoing laparoscopic distal pancreatectomy or open distal pancreatectomy for pancreatic solid pseudopapillary tumor n (%)

Characteristics	LDP (n = 15)	ODP (n = 13)	P value
Harvested lymph nodes	4.6 ± 4.1	6.4 ± 6.2	0.549
Negative surgical margin,	15 (100.0)	13 (100.0)	-
Invasion of peripancreatic tissue	4 (26.7)	2 (15.4)	0.655
Perineural invasion	1 (6.7)	1 (7.7)	1.000
Liver metastasis	0 (0.0)	0 (0.0)	-
Lymphatic metastasis	0 (0.0)	0 (0.0)	-
Invasion of adjacent organs	0 (0.0)	0 (0.0)	-
Angioinvasion	0 (0.0)	0 (0.0)	-

Data are expressed as n (%) or mean ± SD or unless otherwise specified. LDP: Laparoscopic distal pancreatectomy; ODP: Open distal pancreatectomy.