Clinical outcomes of radiation therapy for early-stage gastric mucosa-associated lymphoid tissue lymphoma

Table 1 Patient characteristics n (%)

Characteristic	No. of patients (n = 64)
Gender
Male	38 (59)
Female	26 (41)
Age (yr)
	Median, 49
	Range, 24-75
Lugano staging system
I	53 (83)
II1	11 (17)
Disease location
Cardia	2 (3)
Fundus	5 (8)
Body	35 (55)
Antrum	7 (11)
Diffuse	15 (23)
H. pylori infection
Negative	33 (52)
Positive	31 (48)
Prior treatment
H. pylori eradication	25 (39)
Chemotherapy	9 (14)
Combined	6 (9)
None	24 (38)
Response to prior treatment
Complete histologic remission (CR)	17
Responding residual disease (rRD)	11
No change (NC)	12
Not evaluable	24
Radiation dose	Median, 36 Gy
≥ 40 Gy	18 (28)
36 Gy	38 (59)
30 Gy	8 (13)
RT technique
AP/PA	25 (39)
3-D conformal	39 (61)

H. pylori: Helicobacter pylori; RT: Radiation therapy; AP/PA: Anteroposterior/posteroanterior.

Table 2 Patients with local recurrence after achieving complete remission with radiation therapy

	Initial H. pylori	Initial Tx before RT	DFI (mo)	H. pylori at relapse	Tx after relapse	Final response
Case 1	+	Anti-HP	14	-	Observation	CR
Case 2	-	None	11	-	Observation	CR
Case 3	-	None	26	-	Observation	CR
Case 4	-	None	20	+	Anti-HP	CR
Case 5	-	None	38	+	Anti-HP	CR

H. pylori: Helicobacter pylori; anti-HP: anti-H. pylori antibiotics; CR: Complete remission; DFI: Disease-free interval; Tx: Treatment.