Microscopic colitis: Is it a spectrum of inflammatory bowel disease?

Table 1 Clinical characteristic of patients

Variables	Case 1	Case 2	Case 3	Case 4	Case 5	Case 6
Age at the time of last follow-up (yr)	81	75	62	60	52	36
Gender	Female	Male	Male	Female	Female	Female
Age at diagnosis of UC	65	42	28	46	34	18
Age at diagnosis of LC/CC	79	72	48	54	45	33
Duration of UC when LC/CC was diagnosed	14	30	20	8	11	15
Extent of UC when LC/CC was diagnosed	Extensive colitis	Extensive colitis	Left-sided	Left-sided	Left-sided	Extensive colitis
Extent of LC/CC at diagnosis	Extensive colitis	Extensive colitis	Right-sided	Extensive colitis	Extensive colitis	Extensive colitis
Endoscopic findings at the time of LC/CC diagnosis	Mild generalized redness	Mild erythema at left colon	Normal	Normal	Normal	Mild erythema at distal rectum
Medication at the time of LC/CC diagnosis	Mesalamine	None	Sulfasalazine, 6- mercaptopurine	Mesalamine	Mesalamine	Mesalamine, 6- mercaptopurine
Medications added when LC/CC was diagnosed	None	Sulfasalazine	None	Bismuth	None	None
Outcome on subsequent follow up	Asymptomatic	Asymptomatic	Ulcerative colitis	Asymptomatic	Ulcerative colitis	Ulcerative colitis
Family history of IBD/LC/CC	UC	None	None	None	None	UC
Smoking	Yes	Ex-smoker	No	Yes	Yes	Ex-smoker
History
Alcohol use history	Yes alcoholic	Yes	No	No	Yes	No
History of aspirin/NSAIDS intake	No	Aspirin	No	NSAIDS	No	No
Period of follow up after LC/CC was diagnosed	3 mo	3 yr	10 yr	3 yr	8 yr	3 yr

NSAIDS: Non steroidal anti-inflammatory drugs; CC: Collagenous colitis; LC: Lymphocytic colitis; UC: Ulcerative colitis; IBD: Inflammatory bowel disease.