Reversal of multidrug resistance in gastric cancer cells by CDX2 downregulation

doi:10.3748/wjg.v19.i26.4155

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 19, Issue 26

This Article

Academic Content and Language Evaluation of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Number of Hits and Downloads for This Article

Total Article Views (8231)

All Articles published online

The chart showing PDF series, HTML series, Figures (1-4) series, Tables (1-1) series.

Item

Count

PDF

558

HTML

4446

Figures (1-4)

443

Tables (1-1)

522

Sum=5969

Publishing Process of This Article

The chart showing Browse series, Download series.

Item

Count

Browse

1000

Download

1262

Sum=2262

Jul 14, 2013 (publication date) through Nov 2, 2025

Times Cited of This Article

Times Cited (11)

Journal Information of This Article

Publication Name

World Journal of Gastroenterology

ISSN

1007-9327

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

- Full Article with Cover (PDF)
- Full Article (XML)

Original Article

World J Gastroenterol. Jul 14, 2013; 19(26): 4155-4165
Published online Jul 14, 2013. doi: 10.3748/wjg.v19.i26.4155

Table 1 IC50 values for anticancer drugs in SGC7901/DDP cells

	Doxorubicin (μg/mL)	5-fluorouracil (μg/mL)	Cisplatin (μg/mL)
SGC7901/DDP + siRNA-CDX2	0.12 ± 0.05^a	0.52 ± 0.13^a	0.82 ± 0.13^a
SGC7901/DDP + siRNA-NC	0.33 ± 0.08	4.10 ± 1.25	2.81 ± 0.50
SGC7901/DDP	0.39 ± 0.15	4.05 ± 1.44	3.28 ± 1.03

IC50 values were evaluated by MTT assay. Each experiment was conducted in triplicate. Data are expressed as means ± SD. One-way analysis of variance followed by Dunnett’s multiple comparison tests revealed statistical differences.

^aP < 0.05 for SGC7901/DDP + small interfering RNA (siRNA)-CDX2 cells vs SGC7901/DDP + siRNA-NC cells and SGC7901/DDP cells.

Full Size Table

Citation: Yan LH, Wang XT, Yang J, Lian C, Kong FB, Wei WY, Luo W, Xiao Q, Xie YB. Reversal of multidrug resistance in gastric cancer cells by CDX2 downregulation. World J Gastroenterol 2013; 19(26): 4155-4165
URL: https://www.wjgnet.com/1007-9327/full/v19/i26/4155.htm
DOI: https://dx.doi.org/10.3748/wjg.v19.i26.4155

Yan LH, Wang XT, Yang J, Lian C, Kong FB, Wei WY, Luo W, Xiao Q, Xie YB. Reversal of multidrug resistance in gastric cancer cells by CDX2 downregulation. World J Gastroenterol 2013; 19(26): 4155-4165 [PMID: 23864778 DOI: 10.3748/wjg.v19.i26.4155]

©2004-2025 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA