Role of international criteria in the diagnosis of autoimmune hepatitis

Table 1 Characteristics of patients with autoimmune hepatitis

Parameter	n (%)
Female	40 (66.7)
Male	20 (33.3)
Single	22 (36.7)
Married	38 (63.3)
Educated	46 (76.7)
Uneducated	14 (23.3)
Alcohol intake	3 (5)
Smoking	11 (18.3)
History of blood transfusion	17 (28.3)
History of hospitalization	48 (80)

Table 2 Serological, biochemical and histologic findings in patients with autoimmune hepatitis

Parameter	Result	Range
AST, IU/L	127.8 ± 108.6	17-812
ALT, IU/L	146.0 ± 98.4	14-916
Total bilirubin, mg/dL	2.7 ± 2.2	0.5-8.6
Direct bilirubin, mg/dL	1.3 ± 1.2	0.05-4.3
Alkaline phosphatase, IU/L	499.9 ± 386.2	71-997
White blood cell, No./mm3	6052.4 ± 2461.5	800-13500
Hemoglobin, g/dL	12.1 ± 3.0	7-17
ESR	40.0 ± 28.7	3-95
Platelet count (× 1000), No./mm3	139.2 ± 91.4	36.4-464
Prothrombin time	15.8 ± 3.3	12.5-31
Creatinine, mg/dL	0.8 ± 0.3	0.5-2.1
FBS, mg/dL	106.9 ± 48.6	68-302
Triglyceride, mg/dL	163.2 ± 109.5	50-506
Total cholesterol, mg/dL	208.1 ± 106.3	47-472
Albumin, g/dL	3.8 ± 0.7	2.1-5.1
Grade	5.5 ± 2.7
Stage	3.2 ± 1.5

All values are mean ± SD. ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; ESR: Erythrocyte sedimentation rate; FBS: Fasting blood sugar.

Table 3 Autoimmune hepatitis diagnosis using simplified score and revised International Autoimmune Hepatitis Group criteria

AIH score	Probable AIH	Definite AIH	No AIH
Revised IAHG
Pre-treatment	17.7 ± 1.7	12.8 ± 1.4	7.7 ± 1.5
Post-treatment	19.7 ± 1.4	14.8 ± 1.4	9.7 ± 1.5
Simplified	7.5 ± 0.5	5.6 ± 0.5	3.3 ± 0.6

Data are mean scores ± SD. AIH: Autoimmune hepatitis; IAHG: International Autoimmune Hepatitis Group.