Effects of medical adhesives in prevention of complications after endoscopic submucosal dissection

Table 1 Patient clinical data

	All patients (n = 171)	Group A (medical adhesive group) (n = 89)	Group B (control group) (n = 82)	P value
Age1 (yr)	57.21 ± 12.22	56.47 ± 13.02	58.01 ± 11.31	NS
Gender (male/female)	75/96	39/50	36/46	NS
Lesion location
Esophageal	37	21	16	NS
Gastric	110	58	52	NS
Colorectal	24	10	14	NS
Depth of lesion
Mucosa or submucosa	50	23	27	NS
Muscularis propria	121	66	55	NS

¹Data are expressed as mean ± SD. NS: Not significant.

Table 2 Comparison of treatment duration and length of hospital stay

	Group A (medical adhesive group)	Group B (control group)	P value
Average duration of ESD treatment (min)	59.44 ± 18.46	55.00 ± 21.00	0.143
Average length of hospital stay (d)	8.89 ± 2.33	9.90 ± 3.30	0.021
Average length of hospital stay when patients with delayed bleeding were excluded (d)	8.89 ± 2.33	9.40 ± 2.47	0.172

Data are expressed as mean ± SD. ESD: Endoscopic submucosal dissection.

Table 3 Complications

	Group A (medical adhesive group)	Group B(control group)	P value
Incidence of delayed bleeding	0.00%	4.88%	0.035
Incidence of perforation	10.10%	9.80%	0.938
Location of perforation (n)
Esophageal	1	2
Gastric	7	6
Colorectal	1	0
Perforated lesions
Muscularis propria	7	8
Scar formation	1	0
Non-scar forming lesion	1	0
Incidence of abdominal distension	13.50%	12.20%	0.802
With perforation	8	6
Without perforation	4	4
Difficulty excreting adhesive	2.25%	0.00%