Gastroesophageal reflux disease after diagnostic endoscopy in the clinical setting

Table 1 Baseline clinical and demographic data

LA-classification	NERD	Grade A	Grade B	Grade C	Grade D
n (F)	138 (90)	21 (13)	33 (15)	19 (5)	55 (22)
(%, 95%CI)	(51.9, 45.9-57.8)	(7.9, 5.2-11.8)	(12.4, 9.0-16.0)	(7.1, 4.6-10.9)	(20.7, 16.2-25.9)
Age, yr, mean ± SD (range)	49 ± 12.2 (19-65)	42 ± 12.9 (19-62)	50 ± 11.9 (22-65)	46 ± 12.8 (29-65)	53 ± 8.1 (37-65)
BMI, kg/m2, mean ± SD (range)	28.8 ± -6.4 (19-49)	30 ± 8.5 (21-53)	29.7 ± 6.1 (21-44)	26.3 ± 5.5 (15-35)	28.7± 7.6 (16-53)
Percentage BMI > 30 kg/m2	39.7%	38.9%	43.3%	27.8%	24.5%
PPI at enrolment	61.5%	50%	71%	57.9%	70.4%
Tobacco	25.2%	30%	8.7%	21.4%	7.9%
Alcohol (daily or > 50 g/d)	7.7%	13.3%	23.8%	14.3%	34.2%
Employed	54.4%	66.7%	55%	50%	44.7%
Married	48.6%	40%	52.2%	42.9%	51.3%
Socioeconomically disadvantaged	54.9%	56.3%	50%	43.8%	51.2%

LA: Los-Angeles; NERD: Non erosive gastroesophageal reflux disease; BMI: Body mass index; PPI: Proton pump inhibitor.

Table 2 Baseline comparisons of patients from the different study sites

Variable	RAH-tertiary referral centre (n = 173)	LMH-community Hospital (n = 93)	P value
Age, yr, mean ± SD (range)	48 ± 12.5 (19-65)	51.5 ± 10.2 (23-65)	0.027
Disadvantaged SES	56%	74.4%	< 0.001
LA-Grade NERD	46.8%	61.3%	0.024
LA-Grade C/D	21.4%	6.4%	0.024
Smoking	14.7%	31.3%	0.007
Alcohol (daily or > 5 Std. drinks/d)	17.1%	12.7%	0.701
Male gender	48.6%	60.2%	0.171
BMI > 30 kg/m2	32.1%	44.1%	0.064

SES: Socioeconomic status; LA: Los-Angeles; NERD: Non erosive gastroesophageal reflux disease; BMI: Body mass index; Std.: Standard; RAH: Royal Adelaide Hospital; LMH: Lyell McEwin Hospital.