Evaluation of inflammatory activity in Crohn’s disease and ulcerative colitis

Table 1 Crohn’s disease activity index items and weighting factors

Item (daily sum per week)
Number of liquid or very soft stools
Abdominal pain score in one week (rating, 0-3)
General well-being (rating, 1-4)
Sum of physical findings per week
Arthritis/arthralgia
Mucocutaneous lesions (e.g., erythema nodosum, aphthous ulcers)
Iritis/uveiti
Anal disease (fissure, fistula, etc.)
External fistula (enterocutaneous, vesicle, vaginal, etc.)
Fever over 37.8 °C
Antidiarrheal use (e.g., diphenoxylate)
Abdominal mass (no = 0, equivocal = 2, yes = 5)
47 minus hematocrit (males) or 42 minus hematocrit (females)
1-x (1-body weight divided by a standard weight)

Table 2 Simple endoscopic score for Crohn’s disease

	Values
Variable	0	1	2	3
Size of ulcers	None	Aphthous ulcers (0.1 to 0.5 cm)	Large ulcers (0.5 to 2.0 cm)	Very large ulcers (> 2 cm)
Ulcerated surface	None	< 10%	10%-30%	> 30%
Affected surface	Unaffected surface	< 50%	50%-75%	> 75%
Presence of narrowing	None	Single, can be passed	Multiple, can be passed	Cannot be passed

Table 3 Computed tomography enterography findings of Crohn’s disease activity and chronic disease

Disease activity	Chronic disease
Bowel wall thickening	Submucosal fat deposition
Mural stratification	Sacculations
Mural hyperenhancement	Fibrofatty proliferation
Increased attenuation in the perienteric fat
Engorged vasa recta