Leptin and peroxisome proliferator-activated receptor γ expression in colorectal adenoma

Table 1 Baseline characteristics of subjects

Baseline characteristics	Value
Total patients	30
Sex (male) n (%)	23 (77)
Age, year	44.6 ± 6.5
BMI ( kg/m2)	24.2 ± 3.83
Polyp size (cm)	1.2 ± 0.3
Polyp number	2.2 ± 1.4
Location1n (%)
Left colon	17 (56.7)
Right colon	13 (43.3)
Dysplasia grade n (%)
Low	13 (43.3)
Intermediate/high	17 (56.7)
Pathology n (%)
Tubular	25 (83.0)
Villotubular	5 (17.0)

¹Left colon consists of transverse, descending and sigmoid colon and rectum, and right colon is composed of cecum and ascending colon. BMI: Body mass index.

Table 2 Leptin expression in colorectal adenomas and clinicopathologic characteristics of patients n (%)

	Leptin expression			PPARG expression
Clinicopathologic features	Positive	Negative	P value	Positive	Negative	P value
	17 (56.7)	13 (43.3)		22 (73.3)	8 (26.7)
BMI
≥ 25 kg/m2	11 (36.7)	3 (5.0)	0.024	11 (36.7)	3 (9.9)	0.689
< 25 kg/m2	6 (20.0)	10 (33.3)		11 (36.7)	5 (16.7)
Dysplasia grade
Low	5 (16.7)	9 (30.0)	0.03	9 (29.7)	5 (16.7)	0.295
Intermediate/high	12 (40.0)	4 (13.3)		13 (43.7)	3 (9.9)
Location1
Left colon	11 (36.7)	6 (20.0)	0.794	8 (26.7)	3 (9.9)	0.954
Right colon	6 (20.0)	4 (13.3)		14 (46.7)	5 (16.7)
Histological type
Tubular	14 (46.7)	11 (36.7)	0.869	12 (40.0)	13 (43.4)	0.743
Villotubular	3 (10.0)	2 (6.6)		2 (6.7)	3 (9.9)

¹Left colon consists of transverse, descending and sigmoid colon and rectum, and right colon is composed of cecum and ascending colon. BMI: Body mass index; PPARG: Peroxisome proliferator-activated receptor γ.