Response evaluation of chemotherapy in metastatic colorectal cancer by contrast enhanced ultrasound

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Feb 14, 2012 (publication date) through Oct 31, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Feb 14, 2012; 18(6): 541-545
Published online Feb 14, 2012. doi: 10.3748/wjg.v18.i6.541

Table 1 Time to peak and to peak quotient in liver metastasis

	Date 1	Date 2	Date 3
Time to peak
Responder (CR, PR)
mean ± SD	9.1 ± 2.9	12.1 ± 2.3	14.6 ± 3.9
95% CI	7.3-10.8	10.7-13.6	12.2-17.0
Non-responder (SD¹,PD)
mean ± SD	14.8 ± 3.7	16.7 ± 2.8	16.4 ± 2.6
95% CI	12.8-16.7	15.2-18.2	15.0-17.7
P value compared responder with non-responder	< 0.001	< 0.001	NS
Time to peak quotient
Responder (CR, PR)
mean ± SD	57.5 ± 11.8	80.5 ± 5.4	93.7 ± 9.2
95% CI	50.3-64.6	77.2-83.7	88.2-99.2
Non-responder (SD¹, PD)
mean ± SD	98.7 ± 12.6	100.6 ± 13.3	96.9 ± 9.7
95% CI	92.2-105.2	93.8-107.5	91.9-101.9
P value compared responder with non-responder	< 0.001	< 0.001	NS

NS: Not significant; CR: Complete response; PR: Partial response; SD¹: Stable disease; PD: Progressive disease; CI: Confidence interval.

Citation: Schirin-Sokhan R, Winograd R, Roderburg C, Bubenzer J, Ó NCD, Guggenberger D, Hecker H, Trautwein C, Tischendorf JJW. Response evaluation of chemotherapy in metastatic colorectal cancer by contrast enhanced ultrasound. World J Gastroenterol 2012; 18(6): 541-545
URL: https://www.wjgnet.com/1007-9327/full/v18/i6/541.htm
DOI: https://dx.doi.org/10.3748/wjg.v18.i6.541