Prognostic value of 18-fluorodeoxyglucose positron emission tomography-computed tomography in resectable colorectal cancer

Table 1 Baseline characteristics of the 163 patients

Characteristic	Value
Age (yr), median (range)	60 (30-81)
Male/female, n	98/65
Stage, n
I	23
II	67
III	64
IV	9
Follow-up duration (d), median (range)	756 (419-1355)
Recurrence, n	25
Death, n	3

Table 2 The maximum standardized uptake value and clinicopathologic characteristics

	SUVmax < 8.6 (n = 80)	SUVmax≥8.6 (n = 83)	P value
Age (yr), median (range)	61.0 (37-81)	60.0 (30-81)	0.799
Sex (male), n	47	51	0.872
Stage, n			0.346
I	15	8
II	33	34
III	28	36
IV	4	5
Tumor size (cm), median (range)	4.0 (2-13.5)	4.5 (2.4-9.5)	0.02
T stage, n			0.01
1	5	3
2	12	8
3	59	57
4	4	15
N stage, n			0.955
0	47	44
1	17	24
2	16	15
M stage, n			0.562
0	76	78
1	4	5
Histology			0.54
WD	6	7
MD	71	67
PD		4
Mucinous	3	5
Median follow-up (d)	776	756	0.285
Recurrence, n	14	11	0.509
Death, n	2	1	0.547

SUVmax: Maximum standardized uptake value; WD: Well-differentiated adenocarcinoma; MD: Moderately differentiated adenocarcinoma; PD: Poorly differentiated adenocarcinoma; T: Tumor; N: Node; M: Metastasis.

Table 3 Two-year disease-free survival according to the Kaplan-Meier method

Variable	No. of patients	Two-year DFS (%)	Log-rank P
Age (yr)			0.29
≥ 60	81	90.1
< 60	82	85.4
Sex			0.08
Male	98	83.7
Female	65	93.8
TNM stage			< 0.01
I	23	100
II	67	98.5
III	64	78.1
IV	9	44.4
SUVmax			0.53
≥ 8.6	83	86.7
< 8.6	80	88.8
CEA (ng/mL)			< 0.01
> 5	36	72.2
≤ 5	123	93.5

DFS: Disease-free survival; TNM: Tumor node metastasis; SUVmax: Maximum standardized uptake value; CEA: Carcinoembryonic antigen.

Table 4 Multivariate Cox regression analysis of disease-free survival

Variable	Relative risk	95% CI	P value
SUVmax ≥ 8.6	0.8	0.35-2.16	0.76
T stage (T3, T4)	3.1	0-6.6	0.94
N stage (N2)	9.78	2.01-49.5	0.01
M stage (M1)	2.51	0.78-7.98	0.12
Age ≥ 60 yr	0.6	0.35-2.16	0.35
Male	1.9	0.71-5.15	0.20
CEA > 5 ng/mL	3.2	1.26-8.42	0.02

SUVmax: Maximum standardized uptake value; CEA: Carcinoembryonic antigen; T: Tumor; N: Node; M: Metastasis.