Microencapsulated tumor assay: Evaluation of the nude mouse model of pancreatic cancer

Table 1 Tumor’s volume of subcutaneous implantation

At day post-implantaion (cm3)	Tumor volume
	4th d	11th d	18th d	25th d	32th d	39th d	46th d	53th d
Tumor volume of single cells	0.054 ± 0.038	0.092 ± 0.055	0.139 ± 0.082	0.267 ± 0.155	0.596 ± 0.296	1.188 ± 0.570	2.020 ± 0.989	2.602 ± 1.100
Tumor volume of microencapsulated cells	0.060 ± 0.070	0.083 ± 0.097	0.145 ± 0.140	0.316 ± 0.278	0.758 ± 0.655	1.316 ± 0.927	2.266 ± 1.307	2.794 ± 1.310

Table 2 Number of mice related to the weight of tumor mass at different stages

Different stage (wk)	Group	No. of mice	No. of tumor mass > 500 mg	No. of tumor mass > 1000 mg	Z1	P value1
4th	Single cells	5	1	0	1.7618	0.0643
	Microencapsulation	7	2	3
8th	Single cells	5	2	1	2.1971	0.0221
	Microencapsulation	7	1	6

Data indicate the number of mice in each group that exhibited the characteristic listed.

¹Got by Wilcoxon signed rank sum test.