Mutual regulation between microRNA-373 and methyl-CpG-binding domain protein 2 in hilar cholangiocarcinoma

Table 1 Relationship between miR-373 expression and clinicopathological features

Clinicopathological features	n	ΔCtvalue of miR-373	P value
Age (yr)
< 60	19	27.69 ± 3.76	0.059
≥ 60	29	25.65 ± 4.35
Gender
Male	33	24.43 ± 2.43	0.877
Female	15	29.01 ± 3.76
Tumor size (cm)
< 2	29	25.92 ± 3.64	0.606
≥ 2	31	25.49 ± 2.59
Pathological type
Adenocarcinoma	44	26.71 ± 3.18	0.390
Mucocellulare carcinoma	2	24.63 ± 3.57
Adenosquamous carcinoma	1	23.94
Squamous carcinoma	0
Undifferentiated carcinoma	1	27.91
Cell differentiation
Well	14	19.09 ± 3.46	0.031a
Moderately	23	21.97 ± 1.74
Poorly	11	28.43 ± 4.09
Bismuth classification
Bismuth I	6	24.66 ± 3.31	0.082
Bismuth II	13	27.65 ± 2.71
Bismuth III	17	26.99 ± 4.02
Bismuth IV	12	26.22 ± 3.96
Lymphatic node metastasis
Absent	19	28.59 ± 2.53	0.224
Present	29	25.01 ± 2.64
Clinical stages
I + II	13	18.35 ± 2.62	0.017a
III + IV	35	27.95 ± 3.12

^aP < 0.05 is significant.