ERCP for the treatment of bile leak after partial hepatectomy and fenestration for symptomatic polycystic liver disease

Table 1 Characteristics of 10 patients with polycystic liver disease who underwent endoscopic retrograde cholangiopancreatography management of post-hepatectomy bile leaks

Patient	Duration of diagnosis prior to surgery (yr)	Surgery performed in addition to fenestration	Cholecystectomy performed?	Time to ERCP (d)	Leak site	Sphincterotomy performed?	Outcome
1	30	Extended left hepatectomy1	Yes	8	Not specified2	No	Success on repeat ERCP
2	2	Extended right hepatectomy	Yes	16	Common hepatic duct	No	Died 10 d after ERCP
3	17	Right hepatectomy	Yes	21	Left intrahepatic	No	Success clinically
4	6	Extended right hepatectomy	No	28	Left intrahepatic	No	Success clinically
5	8	Right hepatectomy	Yes	7	No leak seen	No	Success clinically
6	4	Left hepatectomy	Yes	20	Not specified	No	Success clinically
7	4	Right hepatectomy	Yes	15	Left intrahepatic	Yes	Success on repeat ERCP
8	26	Left hepatectomy	No	43	Not specified	Yes	Success clinically
9	30	Extended left hepatectomy	Yes	4	No leak seen	Yes	Success on repeat ERCP
10	20	Left hepatectomy	No	6	Right intrahepatic	Yes	Success on repeat ERCP

¹Extended included removal of segments 4A and/or 4B of the liver;

²Leak noted into percutaneous drain, but no specific site identified. ERCP: Endoscopic retrograde cholangiopancreatography.

Table 2 Risk factors for bile leak development

	Cases(n = 10)	Controls(n = 20)	Effect	P value
Age (yr) (mean ± SD)	48.3 ± 9.7	52.2 ± 9.2	-3.9	0.30
Duration of symptoms (yr) (mean ± SD)	14.7 ± 11.3	13.4 ± 7.6	1.3	0.71
Previous surgery (Y/N) n (%)	3 (30)	4 (20)	OR: 1.71, 95% CI: 0.3-9.78	0.66
Charlson score median (range)	1.5 (0-4)	1.5 (1-5)	No difference	0.60
Wedge resection n (%)	2 (20)	10 (50)	OR: 0.25, 95% CI: 0.04-1.48	0.24
Post-op drains median (range)	1 (1-2)	1 (1-2)	No difference	0.67
Concomitant cholecystectomy n (%)	7 (70)	17 (85)	OR: 0.41, 95% CI: 0.07-2.56	0.37

OR: Odds ratio; CI: Confidence interval; Y/N: Yes/no.