Effect of sumatriptan on gastric emptying: A crossover study using the BreathID system

doi:10.3748/wjg.v18.i26.3415

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Jul 14, 2012 (publication date) through Nov 14, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jul 14, 2012; 18(26): 3415-3419
Published online Jul 14, 2012. doi: 10.3748/wjg.v18.i26.3415

Table 1 Comparison of breath test parameters

	Sumatriptan	Control	P value
T_1/2	131.84 (103.13-168.70)	120.27 (89.61-138.25)	0.0166
T_lag	80.085 (59.23-125.89)	61.11 (39.86-87.05)	0.0125
GEC	3.545 (3.20-3.97)	3.55 (3.19-4.03)	0.6460
β	2.3374 (1.6407-3.8209)	2.0847 (1.4755-2.9269)	0.0284
κ	0.5833 (0.3689-0.7836)	0.6180 (0.4661-0.8872)	0.3329

T_1/2: Time to emptying of 50% of the labeled meal (min); T_lag: Very similar to the percentage dose recovery peak time (min); GEC: Gastric emptying coefficient; β and κ: Regression-estimated constants. A larger (smaller) value of β indicates slower (faster) emptying in the early phase, and a larger (smaller) value of κ indicates faster (slower) emptying in the later phase.

Citation: Sakamoto Y, Sekino Y, Yamada E, Higurashi T, Ohkubo H, Sakai E, Endo H, Iida H, Nonaka T, Fujita K, Yoneda M, Koide T, Takahashi H, Goto A, Abe Y, Gotoh E, Maeda S, Nakajima A, Inamori M. Effect of sumatriptan on gastric emptying: A crossover study using the BreathID system. World J Gastroenterol 2012; 18(26): 3415-3419
URL: https://www.wjgnet.com/1007-9327/full/v18/i26/3415.htm
DOI: https://dx.doi.org/10.3748/wjg.v18.i26.3415