Two-stage resection for malignant colonic obstructions: The timing of early resection and possible predictive factors

Table 1 Baseline demographics

	Group A (n = 19)	Group B (n = 19 )	P value
Gender, male/female	14/5	13/6	0.721
Age (yr)	60.6 ± 13	67.9 ± 14.9	0.117
Pre-diversion sepsis (%)	0	10 (53)	< 0.001
Co-morbidities			0.139
0	10 (53)	4 (21)
1	7 (37)	9 (47)
2	2 (11)	4 (21)
≥ 3	0	2 (10.5)
Days of obstruction	3.6 ± 1	4.8 ± 1.6	0.009
Interval (d)	7.9 ± 1.3	17.8 ± 5.5	< 0.001

Data are presented as n, n (%), mean ± SD or as noted.

Table 2 Post-diversion outcome

	Group A (n = 19)	Group B (n = 19)	P value
Stoma type
T-loop colostomy	19	19
Time to presenting with bowel sounds (d)	1.6 ± 0.5	2.7 ± 1.2	0.001
Time to passage of flatus (d)	1.8 ± 0.4	3 ± 1.4	0.001
Time to removal of the nasogastric tube (d)	1.8 ± 0.8	3.1 ± 1.5	0.002
Time to initiation of oral feeding (d)	2.2 ± 0.6	3.5 ± 1.3	0.001
Complications
Sepsis	0	1 (5)	0.311
Stomal infection	1 (5)	3 (16)	0.290

Data are presented as n, n (%), mean ± SD or as noted.

Table 3 Perioperative data and tumor characteristics

	Group A (n = 19)	Group B (n = 19 )	P value
Type of operation			0.201
Left hemicolectomy	16 (84)	11 (58)
Extended left hemicolectomy	1 (5)	3 (16)
Anterior resection	2 (10)	5 (26)
Operation time (h)	4.9 ± 0.4	5.5 ± 0.7	0.003
Blood loss (mL)	213 ± 149	250 ± 92	0.533
Blood transfusion (mL)	26.3 ± 78.8	39.5 ± 93.7	0.642
Tumor location			0.162
Transverse colon	2 (10)	2 (10)
Descending colon	11 (58)	5 (26)
Descending/ sigmoid colon	2 (10)	7 (37)
Sigmoid colon	4 (21)	5 (26)
Pathological diagnosis
Adenocarcinoma	19	19
Tumor differentiation			0.734
Well or moderate	15 (79)	13 (69)
Poor	3 (16)	4 (21)
Undifferentiated or not known	1 (5.3)	2 (10)
Stage			0.260
II	6 (32)	11 (58)
III	11 (58)	7 (37)
IV	2 (10)	1 (5)

Data are presented as n, n (%), mean ± SD or as noted.

Table 4 Outcome and complications

	Group A (n = 19)	Group B (n = 19)	P value
Hospital stay	21.2 ± 3.2	36.2 ± 17.4	0.001
Ileus > 4 d	1 (5)	2 (10)	0.547
Anastomotic leakage	0	0
Wound infection	4 (21)	5 (26)	0.703
Post-resection sepsis	1 (5)	1 (5)
Other complications			0.548
Urinary tract infection	0	1 (5)
Pneumonia	1 (5)	1 (5)
Upper gastrointestinal bleeding	0	1 (5)

Data are presented as n, n (%), mean ± SD or as noted.