Effect of biologically active fraction of Nardostachys jatamansi on cerulein-induced acute pancreatitis

Table 1 Semi-quantitative analysis of pancreas in acute pancreatitis

Severity score	Inflammation	Edema	Necrosis
Saline	0.5 ± 0.2	0.5 ± 0.2	0.5 ± 0.2
Saline + AP	2.5 ± 0.5a	2.5 ± 0.5a	2.5 ± 0.5a
NJ4 1 + AP	1.5 ± 0.3ac	2.0 ± 0.3a	2.0 ± 0.3a
NJ4 5 + AP	1.5 ± 0.2ac	1.5 ± 0.3ac	1.5 ± 0.2ac
NJ4 10 + AP	1.1 ± 0.1ac	1.0 ± 0.2ac	1.2 ± 0.15ac

Histological sections of the pancreas were scored from 0 (normal) to 3 (severe) for inflammation, edema, and necrosis.

^aP < 0.05 vs the saline treatment;

^cP < 0.05 vs cerulein treatment alone. AP: Acute pancreatitis; NJ: Nardostachys jatamansi.

Table 2 Semi-quantitative analysis of lung in acute pancreatitis

Severity score	Inflammation	Edema
Saline	0.5 ± 0.2	0.5 ± 0.2
Saline + AP	2.5 ± 0.5a	2.5 ± 0.5a
NJ4 1 + AP	1.3 ± 0.4ac	1.8 ± 0.3a
NJ4 5 + AP	1.3 ± 0.3ac	1.6 ± 0.3ac
NJ4 10 + AP	1.1 ± 0.2ac	1.2 ± 0.1ac

Histological sections of the lung were scored from 0 (normal) to 3 (severe) for inflammation, and edema.

^aP < 0.05 vs the saline treatment;

^cP < 0.05 vs cerulein treatment alone. AP: Acute pancreatitis; NJ: Nardostachys jatamansi.