XAF1 is frequently methylated in human esophageal cancer

Table 1 Clinicopathological characteristics and XAF1 methylation status of 40 patients with esophageal cancer n (%)

Clinical parameter	n	XAF1 methylation status		P value
		Methylatedn = 30 (75%)	Unmethylatedn = 10 (25%)	(χ2test)
Age (yr)
< 65	40	30 (75)	10 (25)	1.0
≥ 65	32	24 (75)	8 (25)
Gender
Male	53	40 (75.5)	13 (24.5)	0.8773
Female	19	14 (73.7)	5 (26.3)
Tumor size (cm)
< 5	48	33 (68.8)	15 (31.2)
≥ 5	24	21 (87.5)	3 (12.5)	0.0833
Tumor stage
I	12	6 (50.0)	6 (50.0)	0.081
II	21	17 (81.0)	4 (19.0)
III	6	6 (100.0)	0 (0)
IV	1	1 (100)	0 (0)
Metastasis
Negative	45	33 (73.3)	12 (26.7)	0.6733
Positive	27	21 (77.8)	6 (22.2)

In this 72 patients, only 32 cases with tumor stage history.