Progression of remnant gastric cancer is associated with duration of follow-up following distal gastrectomy

Table 1 Association between clinicopathologic characteristics and initial disease n (%)

		Initial disease
Variables	n	Benign (n= 19)	Cancer (n= 14)	Pvalue
Age (yr) (mean)		70 (51)	66 (49)	0.26
Gender
Male	24	15 (63)	9 (38)
Female	9	4 (44)	5 (56)	0.35
Interval from initial surgery
Year (median)		30 (4-51)	12 (2-22)	< 0.05
Reconstruction of 1st surgery
Billroth-I	16	4 (25)	12 (75)
Billroth-II	16	15 (94)	1 (6)
R-Y	1	0 (0)	1 (100)	< 0.001
Location of RGC
Anastomotic site	11	9 (82)	2 (18)
Suture line	7	2 (29)	5 (71)
Others	15	8 (53)	7 (47)	0.08
Histological type
Differentiated	13	8 (62)	5 (38)
Undifferentiated	20	11 (55)	9 (45)	0.71
Lymphatic invasion
Negative	16	8 (50)	8 (50)
Positive	17	11 (65)	6 (35)	0.39
Venous invasion
Negative	16	8 (50)	8 (50)
Positive	17	11 (65)	6 (35)	0.39
Tumor size
cm (mean)		51 (46)	61 (54)	0.40
Depth of tumor
T1	10	4 (40)	6 (60)
T2, 3, 4	23	15 (65)	8 (35)	0.18
Lymph node metastasis
Negative	20	10 (50)	10 (50)
Positive	13	9 (69)	4 (31)	0.27
Stage
I	17	8 (47)	9 (53)
II, III, IV	16	11 (69)	5 (31)	0.21

Significant values are shown in boldface type. P values were derived from χ² or Fisher's exact test and were considered significant at < 0.05. R-Y: Roux-en Y; RGC: Remnant gastric cancer.

Table 2 Association between clinicopathologic characteristics and reconstruction of 1st surgery n (%)

			Reconstruction at first surgery
Variables		n	Billroth-I(n= 16)	Billroth-II(n= 16)	Pvalue
Age (yr) (mean)			68 (50)	69 (50)	0.64
Gender
	Male	24	13 (54)	11 (46)
	Female	8	3 (38)	5 (63)	0.69
Interval from initial surgery
	Year (median)		12 (2-36)	32 (5-51)	< 0.001
Initial gastric disease
	Benign	19	4 (21)	15 (79)
	Cancer	13	12 (92)	1 (8)	< 0.001
Location of RGC
	Anastomotic site	11	2 (18)	9 (82)
	Suture line	7	5 (71)	2 (29)
	Others	14	9 (64)	5 (36)	0.11
Histological type
	Differentiated	13	8 (62)	5 (38)
	Undifferentiated	19	8 (42)	11 (58)	0.47
Lymphatic invasion
	Negative	15	6 (40)	9 (60)
	Positive	17	10 (59)	7 (41)	0.48
Venous invasion
	Negative	16	8 (50)	8 (50)
	Positive	16	8 (50)	8 (50)	0.72
Tumor size
	mm (mean)		51	56	0.67
Depth of tumor
	T1	10	6 (60)	4 (40)
	T2, 3, 4	22	10 (45)	12 (55)	0.76
Lymph node metastasis
	Negative	14	9 (47)	10 (53)
	Positive	13	7 (54)	6 (46)	1
Stage
	I	17	9 (53)	8 (47)
	II, III, IV	15	7 (47)	8 (53)	1

Significant values are shown in boldface type. P values were derived from χ² or Fisher's exact test and were considered significant at < 0.05. RGC: Remnant gastric cancer.