Copyright
©2012 Baishideng Publishing Group Co.
World J Gastroenterol. May 14, 2012; 18(18): 2197-2202
Published online May 14, 2012. doi: 10.3748/wjg.v18.i18.2197
Published online May 14, 2012. doi: 10.3748/wjg.v18.i18.2197
Treatments groups | ALT (IU/L) | AST (IU/L) | LDH (IU/L) | MDA (nmol/mg) | GSH/GSSH |
Vehicle control | 30 ± 21 | 146 ± 58 | 1504 ± 410 | 0.18 ± 0.11 | 6.045 ± 0.629 |
APAP alone at 500 mg/kg | 8355 ± 3940a | 6482 ± 4018a | 24 627 ± 10975a | 2.15 ± 1.07a | 3.306 ± 0.282a |
5-MOP at 12.5 mg/kg | 1674 ± 1810c | 729 ± 685c | 7220 ± 6317c | 0.98 ± 0.45 | 3.834 ± 0.340 |
5-MOP at 25 mg/kg | 54 ± 39c | 187 ± 149c | 1618 ± 719c | 0.59 ± 0.07c | 5.330 ± 0.421c |
5-MOP at 50 mg/kg | 19 ± 9c | 141 ± 12c | 1394 ± 469c | 0.47 ± 0.06c | 6.180 ± 0.212c |
5-MOP alone at 50 mg/kg | 37 ± 20 | 138 ± 22 | 1471 ± 191 | 0.15 ± 0.09 | 6.858 ± 0.678 |
- Citation: Liu WX, Jia FL, He YY, Zhang BX. Protective effects of 5-methoxypsoralen against acetaminophen-induced hepatotoxicity in mice. World J Gastroenterol 2012; 18(18): 2197-2202
- URL: https://www.wjgnet.com/1007-9327/full/v18/i18/2197.htm
- DOI: https://dx.doi.org/10.3748/wjg.v18.i18.2197