Dual regulatory role for phosphatase and tensin homolog in specification of intestinal endocrine cell subtypes

Table 1 Gene expression changes in the small intestine of Pten^∆IEC mice

Gene description	Gene symbol	Fold	P value
Hairy and enhancer of split 1	Hes1	-1.08	NS
Atonal homolog 1	Math 1	-2.05	NS
Neurogenin 3	Ngn3	-2.07	0.033
Growth factor independent 1	Gfi1	1.07	NS
Neurogenic differentiation 1	NeuroD1	-1.40	0.002
Pancreatic and duodenal homeobox 1	Pdx1	2.15	0.048
Forkhead box O1	FoxO1	-1.95	0.017
Forkhead box a1	Foxa1	2.64	0.017
Forkhead box a2	Foxa2	-1.25	NS

Target expression was quantified relatively to PDGB expression. Fold changes represent the ratio of mean expression values (control/mutant). Negative values indicate reduction in Pten^∆IEC intestines. NS: Non significant fold change (Mann-Whitney test).