Celiac disease: Management of persistent symptoms in patients on a gluten-free diet

Table 1 Demographics and distribution of symptoms in 112 patients referred to our institution with continued symptoms on a gluten-free diet (%)

Male	31
Female	69
Mean age (yr)	48.5
Primary non-responsive	72
Secondary non-responsive	28
Mean years since diagnosis of CD (yr)	3 (range 1-12)
Diarrhea	65
Lethargy/fatigue	43
Abdominal pain	37
Weight loss	23
Nausea and vomiting	10
Symptoms of anemia	10
Two symptoms	49
Three symptoms	20

CD: Celiac disease.

Table 2 Summary of established diagnosis in 100 patients referred to our center with non-responsive celiac disease

Diagnosis	n
Continued dietary gluten	45
Microscopic colitis	11
Bacterial overgrowth	9
Lactose intolerance	7
Inflammatory colitis	7
Irritable bowel syndrome	10
Refractory celiac disease	9
Type I RCD	2
Type II RCD	7
Anorexia nervosa	2
Pancreatic insufficiency	2
Diverticular disease	2
Medication-induced diarrhea	2
Combined variable immunodeficiency	1
Human immunodeficiency virus	1
Colorectal cancer	1
Anorectal dysfunction	1
Incorrect diagnosis of celiac disease	12

RCD: Responsive celiac disease.