Prognostic factors of T4 gastric cancer patients undergoing potentially curative resection

Table 1 Patient characteristics

Variables	n (%)
Age
≤ 68	31 (43.7)
> 68	40 (56.3)
Gender
Male	53 (74.6)
Female	18 (25.4)
Tumor location
Upper 1/3	7 (9.9)
Middle 1/3	28 (39.4)
Lower 1/3	21(29.6)
Tumor size (mean, mm)	20-205 (84)
Type of gastrectomy
Proximal	3 (4.2)
Distal	35 (49.3)
Total	33 (46.5)
Lymph node involvement
Positive	61 (85.9)
Negative	10 (14.1)
Histological type
Differentiated	31 (43.7)
Undifferentiated	40 (56.3)

Table 2 Postoperative complications

	Patients (n = 71)	%
Morbidity	19	26.8
Pancreatic fistula	6	8.5
Anastomosis stricture	5	7.0
Anastomosis leakage	3	4.2
Cholecystitis	3	4.2
Abdominal abscess	2	2.8
Ileus	1	1.4
Mortality	3	4.2

Table 3 Clinicopathological factors and univariate survival analyses

	n	5-yr survival (%)	P
Age (mean: 68.9)
≤ 68	31	45.5	0.415 (NS)
> 68	40	26.2
Gender
Male	53	31.0	0.510 (NS)
Female	18	50.1
Tumor diameter (mm, mean: 84)
≤ 84	39	34.4	0.213 (NS)
> 84	32	33.9
Histological type
Differentiated	31	18.6	0.565 (NS)
Undifferentiaed	40	40.7
Number of lymph node meta
N0 or N1	19	67.4	< 0.05
N2 or N3	52	23.8
MLR (mean: 0.27)
≤ 0.27	46	38.9	0.083 (NS)
> 0.27	25	20.7
Lymphatic invasion
ly0 or ly1	17	49.3	0.453 (NS)
ly2 or ly3	54	29.7
Venous invasion
v0 or v1	53	45.7	< 0.05
v2 or v3	18	9.7
Peritoneal washing cytology
Negative (CY0)	44	47.6	< 0.01
Positive (CY1)	27	15.2

NS: Not significant.

Table 4 Multivariate analysis

	Hazard ratio	95% CI	P
Number of LN meta	1.3104	0.4075-4.2137	0.6501
Venous invasion	0.9642	0.3335-2.7882	0.9464
Peritoneal washing cytology	3.6262	1.3743-9.5683	< 0.01

CI: Confidence interval.