Pancreatic cancer risk variant ABO rs505922 in patients with cholangiocarcinoma

Table 1 Allele and genotype distribution and association tests

ABO rs505922 allele/genotype	Counts of alleles/genotypes
	Controls(2N = 700)	Cases(2N = 360)
C	246 (0.35)	124 (0.34)
T	454 (0.65)	236 (0.66)
CC	50 (0.14)	28 (0.16)
CT	146 (0.42)	68 (0.38)
TT	154 (0.44)	84 (0.46)
Association test	χ2	P
Allele frequency difference test	0.05	0.82
Armitrage’s trend test	0.05	0.83
OR statistics	OR	95% CI
[T][C]	1.03	0.79-1.35
[TT][CC]	0.94	0.57-1.66
[TT][CT + CC]	1.11	0.78-1.60

Patients with cholangiocarcinoma are defined as cases, the [C] allele represents the assumed cholangiocarcinoma risk allele. CI: Confidence interval; OR: Odds ratio.