Sica GS, Iaculli E, Biancone L, Carlo SD, Scaramuzzo R, Fiorani C, Gentileschi P, Gaspari AL. Comparative study of laparoscopic vs open gastrectomy in gastric cancer management. World J Gastroenterol 2011; 17(41): 4602-4606 [PMID: 22147966 DOI: 10.3748/wjg.v17.i41.4602]
Corresponding Author of This Article
Dr. Giuseppe S Sica, MD, PhD, Department of Surgical Sciences, “Tor Vergata” University Hospital, Viale Oxford 81, 00133 Rome, Italy. sica.giuseppe@fastwebnet.it
Article-Type of This Article
Brief Article
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World J Gastroenterol. Nov 7, 2011; 17(41): 4602-4606 Published online Nov 7, 2011. doi: 10.3748/wjg.v17.i41.4602
Table 1 Clinical characteristics of patients
LGS (n = 22)
OGS (n = 25)
P value
Median age, yr (range)
67 (38-75)
68 (54-75)
0.07
Gender (M/F)
13/9
13/12
0.4
BMI, kg/m2 (range)
23 (18-25)
22 (18-26)
0.9
ASA score, median (range)
2 (0-3)
2 (0-3)
0.3
0
5 (23%)
2 (8%)
1
3 (14%)
8 (32%)
2
10 (45%)
10 (40%)
3
4 (18%)
5 (20%)
Tumor location (%)
0.9
Upper
5 (23%)
6 (24%)
Middle
7 (32%)
7 (28%)
Lower
10 (45%)
12 (48%)
Lauren histology (%)
0.7
Intestinal
12 (54%)
12 (48%)
Diffuse
10 (46%)
13 (52%)
pTNM [1997] (%)
0.6
Ib
2 (9%)
2 (8%)
II
9 (41%)
13 (52%)
IIIa/b
10 (45%)
7 (28%)
IV
1 (5%)
3 (12%)
Table 2 Operative findings
LGS (n = 22)
OGS (n = 25)
P value
Type of gastric resection (%)
0.7
Subtotal
17 (77%)
18 (72%)
Total
5 (23%)
7 (28%)
Reconstruction (%)
0.6
Billroth 2
3 (14%)
2 (8%)
Roux-en-Y
19 (86%)
23 (92%)
Lymphadenectomy (%)
1
D1
2 (9%)
2 (8%)
D2
20 (91%)
23 (92%)
Lymph-nodes retrived
29 ± 7
30 ± 9
0.5
Table 3 Tumour recurrence and survival analyses
LGS(n = 22)
OGS(n = 25)
P value
Overall 5 yr mortality rate
12 (54.5%)
14 (56%)
1
Cancer-related 5 yr mortality rate
11 (50%)
13 (52%)
1
FU (5 yr) accomplishment
20 (91%)
23 (92%)
1
Type of recurrence
0.9
Port-site M
0 (0%)
Locoregional/carcinosis
2 (18%)
4 (31%)
Hepatic M
6 (55%)
6 (46%)
Distant M
3 (27%)
3 (23%)
Median survival, mo (range)
39 (12-60)
38 (11-60)
0.7
Disease free interval, mo (range)
28 (12-60)
26 (10-60)
0.6
Table 4 Survival analyses by Kaplan-Meier method
AGC + T1b (n = 47)
AGC (n = 43)
Cancer related survival probability analyses (P)
0.81
0.92
Overall survival probability analyses (P)
0.83
0.92
Citation: Sica GS, Iaculli E, Biancone L, Carlo SD, Scaramuzzo R, Fiorani C, Gentileschi P, Gaspari AL. Comparative study of laparoscopic vs open gastrectomy in gastric cancer management. World J Gastroenterol 2011; 17(41): 4602-4606