Aberrant methylation of the 3q25 tumor suppressor gene PTX3 in human esophageal squamous cell carcinoma

Table 1 Clinical features of esophageal squamous cell carcinoma patients and their expression status for pentraxin 3 n (%)

Clinicopathological features	PTX3 expression
	Positive	Negative	P value
Cases	24 (30)	55 (70)
Gender
Male	16 (30)	38 (70)	0.831
Female	8 (32)	17 (68)
Age (mean, yr)	59.6	61.2	0.510
Smoker	12 (32)	26 (68)	0.823
Non-smoker	12 (29)	29 (71)
Depth of invasion			0.315
T1, T2	16 (35)	30 (65)
T3, T4	8 (24)	25 (76)
Lymph node metastasis			0.311
Positive	4 (20)	16 (80)
Negative	20 (34)	39 (66)
TNM classification			0.012
I	9 (23)	20 (77)
IIa	10 (35)	19 (65)
IIb	2 (29)	5 (71)
III	1 (11)	8 (89)
IV	2 (67)	3 (23)

TNM: TNM classification of malignant tumours, T describes the size of the tumor and whether it has invaded nearby tissue, N describes regional lymph nodes that are involved, M describes distant metastasis.