Diagnostic efficacy of gadoxetic acid-enhanced MRI for hepatocellular carcinoma and dysplastic nodule

Table 1 Correlation of histological grade and hemodynamic pattern

		Hemodynamic pattern			Total
		A	B	C
Histological grade	DN	2	1	0	3
	Well	162	82	81	32
	Mod.	7	3	262	36
	Poor	1	0	102	11
Total		26	12	44	82

Hemodynamic patterns; A: Isodensity on computed tomography (CT) during arterial portography (CTAP) and isodensity or low density on CT hepatic arteriography (CTHA); B: Slightly low density on CTAP and isodensity or low density on CTHA; C: Low density on CTAP and high density on CTHA.DN: Dysplastic nodule; Well: Well differentiated hepatocellular carcinoma (HCC); Mod: Moderately differentiated HCC; Poor: Poorly differentiated HCC.

¹Significantly lower frequency;

²Significantly higher frequency.

Table 2 Correlation between histological grade and signal intensity in the hepatobiliary phase

		Hepatobiliary phase			Total
		Hyper.	Iso.	Hypo.
Histological grade	DN	0	22	11	3
	Well	1	3	28	32
	Mod.	1	01	35	36
	Poor	0	0	11	11
Total		2	5	75	82

DN: Dysplastic nodule; Well: Well differentiated hepatocellular carcinoma (HCC); Mod: Moderately differentiated HCC; Poor: Poorly differentiated HCC. Hyper: Hyperintensity; Iso: Isointensity; Hypo: Hypointensity.

¹Significantly lower frequency;

²Significantly higher frequency.

Table 3 Histological grade and signal intensity in the hepatobiliary phase in lesions which maintained portal blood flow

		Hepatobiliary phase			Total
		Hyperintensity	Isointensity	Hypointensity
Histological grade	DN	0	2b	0a	2
	Well	1	0	15	16
	Mod.	0	0	7	7
	Poor	0	0	1	1
Total		1	2	23	26

DN: Dysplastic nodule; Well: Well differentiated hepatocellular carcinoma (HCC); Mod: Moderately differentiated HCC; Poor: Poorly differentiated HCC.

^aSignificantly lower frequency, P < 0.05;

^bSignificantly higher frequency, P < 0.05.

Table 4 Histological grade and signal intensity in the hepatobiliary phase in lesions with decreased portal blood flow

		Hepatobiliary phase		Total
		Isointensity	Hypointensity
Histological grade	DN	0	1	1
	Well	1	7	8
	Mod.	0	3	3
	Poor	0	0	0
Total		1	11	12

DN: Dysplastic nodule; Well: Well differentiated hepatocellular carcinoma (HCC); Mod: Moderately differentiated HCC; Poor: Poorly differentiated HCC.

Table 5 Histological grade and signal intensity in the hepatobiliary phase in lesions which lacked portal blood flow

		Hepatobiliary phase			Total
		Hyperintensity	Isointensity	Hypointensity
Histological grade	DN	0	0	0	0
	Well	0	2	6	8
	Mod.	1	0	25	26
	Poor	0	0	10	10
Total		1	2	41	44

DN: Dysplastic nodule; Well: Well differentiated hepatocellular carcinoma (HCC); Mod: Moderately differentiated HCC; Poor: Poorly differentiated HCC.

Table 6 Correlation of signal intensity on pre-contrast T1WI, T2WI and hepatobiliary phase

		Hepatobiliary phase			Total
		Hyperintensity	Isointensity	Hypointensity
T1WI	Hyperintensity	1	5b	21a	27
In-phase	Isointensity	0	0	27	27
	Hypointensity	1	0	27	28
T1WI Opposed phase	Hyperintensity	1	2	17	20
	Isointensity	0	3	23	26
	Hypointensity	1	0	35	36
T2WI	Hyperintensity	1	1	42	44
	Isointensity	0	4	27	31
	Hypointensity	1	0	6	7

^aSignificantly lower frequency, P < 0.05;

^bSignificantly higher frequency, P < 0.05.