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World J Gastroenterol. Jul 21, 2011; 17(27): 3242-3247
Published online Jul 21, 2011. doi: 10.3748/wjg.v17.i27.3242
Published online Jul 21, 2011. doi: 10.3748/wjg.v17.i27.3242
Table 1 Baseline demographic and clinical characteristics of patient population
Treatment group | Placebo group | |
No. of patients | 98 | 97 |
Age (yr, mean ± SD) | 49.2 ± 14.1 | 45.5 ± 14.9 |
Gender (male/female) | 47/51 | 42/55 |
Total scores of symptoms before treatment (mean ± SD) | 9.0 ± 2.8 | 8.4 ± 2.6 |
Table 2 Total efficacy of Helicobacter pylori eradication therapy in functional dyspepsia patients with Helicobacter pylori infection n (%)
Group | n | Clinical recovery | Significant improvement | Improvement | Invalidation | Total effective rates | |
PP | Treatment group | ||||||
Patients with successful H. pylori eradication | 72 | 11 (15.3) | 21 (29.1) | 30 (41.7) | 10 (13.9) | 32 (44.4)a | |
Patients receiving H. pylori eradication therapy | 84 | 12 (14.3) | 24 (28.6) | 33 (39.3) | 15 (17.8) | 36 (42.9)a | |
Placebo group | 89 | 3 (3.4) | 16 (18.0) | 34 (38.2) | 36 (40.4) | 19 (21.4) | |
ITT | Treatment group | 98 | 12 (12.2) | 24 (24.5) | 33 (33.7) | 29 (29.6) | 36 (36.7)a |
Placebo group | 97 | 3 (3.1) | 16 (16.5) | 34 (35.1) | 44 (45.4) | 19 (19.6) |
Table 3 Respective efficacy for six common symptoms in functional dyspepsia patients n (%)
Group | n | Effective rates | ||||||
Postprandial distress syndrome | Epigastric pain syndrome | |||||||
Postprandial fullness | Early satiety | Nausea | Belching | Epigastric pain | Epigastric burning | |||
PP | Treatment group | |||||||
Patients with successful H. pylori eradication | 72 | 23 (46.0) | 18 (36.0) | 21 (52.5) | 15 (33.3) | 44 (77.2)a | 41 (82.0)a | |
Patients receiving H. pylori eradication therapy | 84 | 24 (41.4) | 19 (33.3) | 23 (50.0) | 16 (31.4) | 48 (73.8)a | 46 (80.7)a | |
Placebo group | 89 | 24 (39.3) | 16 (27.1) | 18 (39.1) | 16 (31.4) | 26 (38.2) | 21 (38.2) | |
ITT | Treatment group | 98 | 24 (34.8) | 19 (27.9) | 23 (41.1) | 16 (26.7) | 48 (60.8)a | 46 (65.7)a |
Placebo group | 97 | 24 (34.8) | 16 (23.9) | 18 (35.3) | 16 (27.1) | 26 (33.3) | 21 (31.8) |
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Citation: Lan L, Yu J, Chen YL, Zhong YL, Zhang H, Jia CH, Yuan Y, Liu BW. Symptom-based tendencies of
Helicobacter pylori eradication in patients with functional dyspepsia. World J Gastroenterol 2011; 17(27): 3242-3247 - URL: https://www.wjgnet.com/1007-9327/full/v17/i27/3242.htm
- DOI: https://dx.doi.org/10.3748/wjg.v17.i27.3242