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©2011 Baishideng Publishing Group Co.
World J Gastroenterol. Jun 7, 2011; 17(21): 2602-2610
Published online Jun 7, 2011. doi: 10.3748/wjg.v17.i21.2602
Published online Jun 7, 2011. doi: 10.3748/wjg.v17.i21.2602
References | Dysplasia and related lesions (from Rugge et al[40], modified) |
Takagi et al[15] | Benign |
Borderline | |
Carcinoma | |
Nagayo[14] | Atypical |
Borderline | |
Probable cancer | |
Definitive cancer | |
Grundmann[2] | Low-grade GED |
High-grade GED | |
Invasive cancer | |
Oehlert et al[5] | Slight GED |
Moderate GED | |
Severer GED | |
Invasive cancer | |
Morson et al[4] | Regenerative |
Mild GED | |
Moderate GED | |
Severe GED | |
Invasive cancer | |
Ming et al[7] | Grade 1 GED |
Grade 2 GED | |
Grade 3 GED | |
Grade 4 GED | |
Invasive cancer | |
Japanese classification of gastric carcinoma[16] | Group I lesions |
Group II lesions | |
Group III-IV lesions | |
Group V lesions | |
Goldstein et al[9] | Reactive |
Indefinite for GED | |
Low-grade GED | |
High-grade GED | |
Invasive cancer | |
Padova classification | Negative |
Indefinite for dysplasia | |
Noninvasive neoplasia | |
Suspect for invasive carcinoma | |
Invasive carcinoma | |
Vienna classification | Negative |
Indefinite for dysplasia | |
Low grade neoplasia | |
High grade neoplasia | |
Invasive neoplasia |
Histology | Feature | Low-grade dysplasia | High-grade dysplsia | Carcinoma |
Structural atypia | Gland size | Uniform | Variable | Variable |
Gland arrangement | Regular | Slightly irregular | Irregular | |
Glandular crowding | Slight | Moderate | Marked | |
Glandular transition to surrounding mucosa | No | No | No | |
Glandular branching/budding | Focal | Prominent | Prominent | |
Glandular cribriform | No | Yes | Yes | |
Surface maturation | No | No | No | |
Nuclear atypia | Shape | Elongated | Elongated and/or irregular | Oval/round |
Pseudostratification | Basal 1/2 | Over basal 1/2 | Irregular | |
Membrane | Thin | Thick | Uneven | |
Hyperchromasia | Hyperchromatic even | Hyperchromatic irregular | Vesicular | |
Pleomorphism | No | Mild | Moderate to marked | |
Prominent nucleoli | Absent | Present | Present | |
Loss of polarity | No | No/yes | Yes | |
Stroma | Invasion | No | No | Yes |
Agreement rate (%) | Before (%) | After (%) |
0-50 | 16 (38.1) | 1 (2.4) |
51-60 | 13 (31.0) | 4 (9.5) |
61-70 | 3 (7.1) | 8 (19.0) |
71-80 | 5 (11.9) | 6 (14.3) |
81-90 | 3 (7.1) | 6 (14.3) |
91-100 | 2 (4.8) | 17 (40.5) |
Total | 42 (100) | 42 (100) |
- Citation: Kim JM, Cho MY, Sohn JH, Kang DY, Park CK, Kim WH, Jin SY, Kim KM, Chang HK, Yu E, Jung ES, Chang MS, Joo JE, Joo M, Kim YW, Park DY, Kang YK, Park SH, Han HS, Kim YB, Park HS, Chae YS, Kwon KW, Chang HJ, Pathologists TGPSGOKSO. Diagnosis of gastric epithelial neoplasia: Dilemma for Korean pathologists. World J Gastroenterol 2011; 17(21): 2602-2610
- URL: https://www.wjgnet.com/1007-9327/full/v17/i21/2602.htm
- DOI: https://dx.doi.org/10.3748/wjg.v17.i21.2602