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©2011 Baishideng Publishing Group Co.
World J Gastroenterol. Jan 14, 2011; 17(2): 236-241
Published online Jan 14, 2011. doi: 10.3748/wjg.v17.i2.236
Published online Jan 14, 2011. doi: 10.3748/wjg.v17.i2.236
Table 1 Patient characteristics
| Variable | n (%) |
| Mean age (yr, range) | 49 ± 9 (20-80) |
| Gender | |
| Female | 272 (27.59) |
| Male | 714 (72.41) |
| Chronic liver disease | |
| Chronic viral hepatitis B | 506 (51.32) |
| Chronic viral hepatitis C | 23 (2.33) |
| HBV related liver cirrhosis | 450 (45.64) |
| HCV related liver cirrhosis | 7 (0.71) |
| Place of residence | |
| Seoul | 389 (39.45) |
| Gyeonggi-do | 274 (27.79) |
| Metropolitan cities | 101 (10.24) |
| Other provinces | 223 (22.62) |
| Prevalence of IgG anti-HAV | 854 (86.61) |
Table 2 Prevalence of IgG anti-hepatitis A virus in patients with hepatitis B virus vs those with hepatitis C virus infection n (%)
| Age (yr) | Anti-HAV/HBV | Anti-HAV/HCV |
| 20-30 | 3/43 (6.98) | 0 |
| 31-40 | 58/112 (51.79) | 0/2 (0) |
| 41-50 | 325/351 (92.59) | 6/7 (85.71) |
| 51-60 | 378/387 (97.67) | 12/12 (100) |
| ≥ 61 | 63/63 (100) | 9/9 (100) |
Table 3 Prevalence of IgG anti-hepatitis A virus according to gender, the status of liver disease and the place of residence
| Characteristics | Anti-HAV positivity, n (%) | P value |
| Sex | 0.049 | |
| Male | 609/714 (85.29) | |
| Female | 245/272 (90.07) | |
| Status of liver disease | < 0.001 | |
| Chronic viral hepatitis | 425/529 (80.34) | |
| Liver cirrhosis | 429/457 (93.87) | |
| Place of residence | < 0.001 | |
| Seoul | 311/389 (79.95) | |
| Gyeonggi-do | 241/274 (87.96) | |
| Metropolitan cities | 96/101 (95.05) | |
| Other provinces | 206/223 (92.38) |
Table 4 Factors affecting seropositivity for IgG anti-hepatitis A virus on the multivariable analysis
| Characteristics | Anti-HAV positivity, n (%) | OR (95% CI) | P value |
| Age (≥ 40 yr) | 809/852 (94.95) | 33.44 (20.14-55.52) | < 0.001 |
| Female | 245/272 (90.07) | 2.07 (1.16-3.71) | 0.014 |
| Etiology | 0.487 | ||
| HBV | 827/956 (86.51) | 1 | |
| HCV | 27/30 (90) | 0.61 (0.15-2.47) | |
| Status of liver disease | 0.075 | ||
| Chronic viral hepatitis | 425/529 (80.34) | 1 | |
| Liver cirrhosis | 429/457 (93.87) | 1.64 (0.95-2.82) | |
| Place of residence | 0.035 | ||
| Seoul | 311/389 (79.95) | 1 | |
| Gyeonggi-do | 241/274 (87.96) | 1.51 (0.86-2.66) | 0.153 |
| Metropolitan cities | 96/101 (95.05) | 4.11 (1.37-12.35) | 0.012 |
| Other provinces | 206/223 (92.38) | 1.84 (0.93-3.65) | 0.080 |
- Citation: Cho HC, Paik SW, Kim YJ, Choi MS, Lee JH, Koh KC, Yoo BC, Son HJ, Kim SW. Seroprevalence of anti-HAV among patients with chronic viral liver disease. World J Gastroenterol 2011; 17(2): 236-241
- URL: https://www.wjgnet.com/1007-9327/full/v17/i2/236.htm
- DOI: https://dx.doi.org/10.3748/wjg.v17.i2.236