Unusual histopathological findings in appendectomy specimens: A retrospective analysis and literature review

Table 1 General characteristics of the 54 patients with abnormal pathological findings

Patients’ characteristics	Results	Rate (%)
Age (yr) (range)	32.2 ± 15.1 (15-84)
Sex
Male	30	55.50
Female	24	44.50
WBC (K/UL) (range)	11.7 ± 4.9 (4.5-26.7)
Histopathologic findings	54
E.vermicularis	37	68.50
Tuberculosis	2	3.70
Carcinoid	5	9.20
Goblet-cell carcinoid	1
Mucocele	2	3.70
Mucinous cystadenoma	4	7.40
Eosinophilic infiltration	2	3.70
Neurogenic hyperplasia	1
Follow-up (mo) (range)	10.4 ± 12.4 (1-54)
Surgical Approach
Appendectomy	52	96.30
Right hemicolectomy	2	3.70
Recurrence	0

Table 2 Clinicopathological characteristics of the six patients with primary appendicular tumors

Age	Sex	Tumor size (mm)	Location	Treatment	Pathology	Parietal spread	Follow-up (mo)
43	F	5	Distal	Appendectomy	Carcinoid	Serosa	54
42	F	10	Distal	Appendectomy	Carcinoid	Serosa	33
23	F	6	Distal	Appendectomy	Carcinoid	Subserosa	15
39	M	4	Distal	Appendectomy	Carcinoid	Submucosa	1
36	M	10	Distal	Appendectomy	Goblet cell	M.Propria	3
26	M	6	Distal	Appendectomy	Carcinoid	Subserosa	1

Table 3 Distribution of the 1366 cases defined as “unusual findings” according to etiological causes

Total patients	1366 (1366/80 698 = 1.7%)
Unusual findings	1366	1.7%
Enterobius vermicularis	389	28.4%
Carcinoid	287	21.0%
Schistosomiasis	174	12.7%
Amoebic appendicitis	118	8.6%
Mucinous cystadenoma (+mucocele)	72	5.2%
Ascaris lumbricoides	39	2.8%
Tuberculous appendicitis	34	2.5%
Endometriosis	41	3.0%
Goblet-cell carcinoid	28	2.0%
Trichuris trichiura	22	1.6%
Idiopathic granulomatous appendicitis	35	2.5%
Crohn disease	18
Lymphoma	14
Primary adenocarcinoma	11
Mucinous cystadenocarcinoma	9
Actinomycosis	8
Melanosis	8
Secondary adenocarcinoma	7
Dysplastic change	7
Villous adenoma	6
Hyperplastic polyp	5
Taeniasis	8
GIST (+leiomyoma)	5
Balantidium coli	3
Tubulovillous adenoma	3
Eosinophilic granuloma	3
Neurogenic hyperplasia	2
Tubular adenoma	2
Leukaemia	4
Blastocystis hominis	1
Adenovirus	1
Strongyloides stercoralis	1
Yersinia enterocolitica	1