Brief Article
Copyright ©2011 Baishideng Publishing Group Co.
World J Gastroenterol. Mar 14, 2011; 17(10): 1336-1342
Published online Mar 14, 2011. doi: 10.3748/wjg.v17.i10.1336
Table 1 Baseline characteristics of 38 patients
Average age (yr), mean ± SD (range)59.9 ± 11.5 (27-80)
Gender
Male:Female20:18
Median interval duration after initial diagnosis (yr)1
Type of GIMAll complete GIM
Positive rapid urease test in 1st endoscopy12/38
Positive rapid urease test in 2nd endoscopy8/26
Dyspeptic symptoms5/38
SmokingNone
Family history of gastric cancerNone
Significant underlying disease5/38
Table 2 Validity scores with confidence intervals of the first endoscopic targeting biopsy for gastric intestinal metaplasia, mean (range)
CriteriaSensitivity (%)Specificity (%)PPV (%)NPV (%)LR + (%)
LBC70.59 (59.57-79.72)83.22 (75.75-88.75)71.43 (60.37-80.49)82.64 (75.24-88.25)4.21 (2.85-6.21)
VP29.41 (20.28-40.43)97.90 (93.51-99.45)89.28 (70.63-97.19)70.00 (63.06-76.16)14.02 (4.36-45.03)
LLC17.65 (10.53-27.75)95.10 (89.79-97.84)68.18 (45.12-85.26)66.02 (59.06-72.36)3.60 (1.53-8.48)
All criteria78.82 (68.34-86.64)82.51 (75.08-88.16)72.83 (62.38-81.33)86.76 (79.63-98.73)4.51 (3.11-6.55)
Table 3 Validity scores with confidence intervals of the second endoscopic targeting biopsy for gastric intestinal metaplasia, mean (range)
CriteriaSensitivity (%)Specificity (%)PPV (%)NPV (%)LR + (%)
LBC82.61 (68.05-91.68)92.73 (85.74-96.58)82.61 (68.05-91.68)92.73 (85.74-96.58)11.36 (5.75-22.42)
VP21.74 (11.45-36.76)98.15 (92.81-99.67)83.33 (50.88-97.06)74.65 (66.53-81.40)11.74 (2.67-51.48)
LLC43.48 (29.25-58.79)99.07 (94.20-99.95)95.24 (74.13-99.75)80.45 (72.49-86.61)46.95 (6.49-339.58)
ALL91.30 (78.31-97.17)89.09 (81.36-93.98)77.78 (64.05-87.52)96.07 (89.69-98.73)8.37 (4.87-14.38)