Brief Article
Copyright ©2011 Baishideng Publishing Group Co.
World J Gastroenterol. Jan 7, 2011; 17(1): 98-104
Published online Jan 7, 2011. doi: 10.3748/wjg.v17.i1.98
Table 1 Patient characteristics
FlexusHanaroWallstentAll stents
No. of patients14211954
Sex (M/F)5/99/129/1023/31
Median age (range)75 (59-86)69 (54-83)73 (60-83)71 (54-86)
Indication
Pancreatic cancer712928
Biliary cancer33410
Hilar metastatic lymphadenopathy1427
Papillary tumor3238
Hepatocellular carcinoma11
Hepatic metastases1326
Prior plastic stent5229
Presentation of first occlusion
Painless jaundice312823
Cholangitis1191131
Cause of obstruction
Ingrowth7161235
Overgrowth45514
Sludge and/or debris325
Median time to first occlusion (range) (d)228.5 (178-398)248 (74-582)176 (98-754)242.5 (7-754)
Type of intervention for first occlusion
Self-expanding metal stent515525
Plastic stent661224
Mechanical cleaning325
Table 2 Outcomes of interventions and financial cost in the course of treatment of first self-expanding metal stent occlusion, median (range) (d)
Plastic stentSecond SEMSMechanical cleaningAll typesP
Intervention for first occlusion
No. of patients2425554
Νo further interventions required
No. of patients13 (54.2%)17 (68%)1 (20%)31 (57.4%)
Survival after first occlusion without further interventions84 (40-179)116 (62-227)3997 (39-227)
Further intervention(s) required
No. of patients11 (45.8%)8 (32%)4 (80%)23 (42.6%)
Types of intervention11 plastic stents insertion5 plastic stents insertion3 plastic stents insertion19 plastic stents insertion
3 mechanical cleaning1 insertion of SEMS1 insertion of SEMS
3 mechanical cleaning
Time to second occlusion (d)91 (60-74)144 (26-331)112 (21-180)96 (21-331)
Overall second stent patency106 (39-645)133 (26-331)0.856
Second stent patency88 (40-179)133 (26-331)< 0.001
Survival after first occlusion106 (40-645)177 (60-870)210 (39-390)142 (39-870)0.180
Number of interventions per patient1 (1-5)1 (1-4)2 (1-3)1 (1-5)0.199
Cost per patient in euros590 (380-2550)2170 (1870-3620)1020 (380-2550)1685 (380-3620)< 0.001