Colorectal cancer prognosis twenty years later

Table 1 Characteristics of the patients n (%)

	Group I (n = 1119)	Group II (n = 871)	P value
Age mean (SD)	66.7 (12.4)	69.1 (11.5)	0.000
Sex			0.027
Males	638 (57)	531 (61)
Females	481 (43)	340 (39)
Tumor localization
Distal to splenic flexure	831 (75)	644 (74)
Proximal to splenic flexure	272 (25)	227 (26)
TNM			0.11
I	190 (17)	122 (14)
II	403 (36)	348 (40)
III	302 (27)	244 (28)
IV	224 (20)	157 (18)
Tumor differentiation			0.000
Poor	45 (4)	70 (8)
Well-moderate	1074 (96)	801 (92)
Receiving chemotherapy	190 (17)	409 (46.9)	0.000

Table 2 Mortality variation in relation to 4 independent risk factors

	Hazard ratio (95% CI)
Stage
II vs I	1.6 (1.2–2.1)
III vs I	3.5 (2.7–4.6)
IV vs I	13.7 (10.4-18.0)
Group
Ivs II	2.0 (1.7–2.4)
Chemotherapy
No vs Yes	1.6 (1.3–1.9)
Grade
I, II vs III	1.5 (1.1–1.9)

Table 3 Comparison of age, rectal localization, post-surgery mortality and administration of chemo and/or radiotherapy n (%)

	Stage I		Stage II		Stage III		Stage IV
	Group I (n = 190)	Group II (n = 122)	Group I (n = 403)	Group II (n = 348)	Group I (n = 302)	Group II (n = 244)	Group I (n = 224)	Group II (n = 157)
Age	66.7	70	66.7	70	66.7	70	67.5	70
Rectal localization	93 (49)	65 (44)	121 (30)	115 (33)	103 (34)	81 (33)	67 (30)	49 (31)
Postoperative mortality	17 (9)	2 (2)	20 (5)	7 (2)	21 (7)	5 (2)	29 (13)	6 (4)
Chemotherapy and/or radiotherapy	10 (5)	10 (8)	48 (12)	90 (26)	91 (30)	137 (56)	54 (24)	55 (35)