Curcumin suppresses gastric NF-κB activation and macromolecular leakage in Helicobacter pylori-infected rats

Table 1 Demonstrated level of Helicobacter pylori colonization and gastric inflammation scores

Group	No.	Level of H. pylori colonization					Score of gastric inflammation
		0	1	2	3	4	0	1	2	3
Control	5	5	-	-	-	-	5	-	-	-
Cur	5	5	-	-	-	-	5	-	-	-
Hp	5	-	5	-	-	-	-	3	2	-
Hp + curI	5	-	5	-	-	-	3	2	-	-
Hp + curII	5	-	3	2	-	-	3	2	-	-

Level of Helicobacter pylori (H. pylori) colonization: Score 0 = no H. pylori detected; Score 1 = mild colonization in some gastric crypts; Score 2 = mild colonization in most gastric crypts; Score 3 = moderate colonization in some gastric crypts; Score 4 = dense colonization in some gastric crypts. Score of gastric inflammation: Score 0 = normal gastric tissue; Score 1 = mild inflammation and histopathology changes; Score 2 = moderate inflammation and histopathology changes; Score 3 = marked inflammation and histopathology changes. Control: Control rats; Cur: Control rats supplemented with 600 mg/kg curcumin; Hp: H. pylori-infected rats; Hp + curI: H. pylori-infected rats supplemented with 200 mg/kg curcumin; Hp + curII: H. pylori-infected rats supplemented with 600 mg/kg curcumin.