Impairment of pre-mRNA splicing in liver disease: Mechanisms and consequences

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Jul 7, 2010 (publication date) through Nov 16, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jul 7, 2010; 16(25): 3091-3102
Published online Jul 7, 2010. doi: 10.3748/wjg.v16.i25.3091

Table 1 Examples of genes with altered splicing in liver carcinogenesis

Gene	Function	Selected ref.
DNMT3b4	DNA methyltransferase	[43,44]
MDM2	E3 ubiquitin ligase	[47]
Aurora kinase B Sv2	Serine/Threonine kinase	[45,46]
Hugl-1	Tumor suppressor	[49]
Tensin 2var3	Focal adhesion	[48]
Cadherin 17	Cell surface adhesion	[55]
MAD1 (β)	Spindle-assembly checkpoint	[50]
KLF6	Tumor suppressor	[36]
SVH	Unknown	[52]
p73	Tumor suppressor	[37,72]

Citation: Berasain C, Goñi S, Castillo J, Latasa MU, Prieto J, Ávila MA. Impairment of pre-mRNA splicing in liver disease: Mechanisms and consequences. World J Gastroenterol 2010; 16(25): 3091-3102
URL: https://www.wjgnet.com/1007-9327/full/v16/i25/3091.htm
DOI: https://dx.doi.org/10.3748/wjg.v16.i25.3091