Clinical features of hepatitis B virus-related hepatocellular carcinoma

Table 1 Carcinogenic factors involved in hepatocellular carcinoma in patients with type B cirrhosis[1]

Variable	n	Univariate analysis			Multivariate analysis
		P-value1	RR2	95% CI	P-value3	RR2	95% CI
ALT (IU/L)
≥ 100	14	0.0083	2.044	1.098-4.677	0.025	4.525	1.202-17.030
< 100	51		1.000			1.000
LDH (IU/L)
≥ 480	30	0.0138	2.000	0.878-4.558	NS (0.081)	2.880	0.881-9.412
< 480	35		1.000			1.000
HBV-DNA (LGE/mL)
≥ 3.7	46	0.0082	2.836	1.269-6.340	0.014	7.712	1.511-39.365
< 3.7	19		1.000			1.000

¹P-values were obtained by using the log-rank test;

²Relative risks were calculated by comparing classes using a Cox regression analysis;

³P-value were obtained by using a Cox regression analysis. HBV: Hepatitis B virus; ALT: Alanine aminotransferase; LDH: Lactate dehydrogenase; NS: Not significant.