Anal transition zone in the surgical management of ulcerative colitis

Table 1 Adenocarcinoma after RPC IPAA for UC¹

Reference	Yr	RPC IPAA	Preoperative diagnosis	Pathological diagnosis	Yr to CA2	Site of carcinoma
Ravitch	1984	HS	NR	NR	NR	NR
Stern	1990	HS	Dysplasia	HGD rectum	3	Pouch
Puthu	1992	NR	NR	NR	6	NR
Rodriguez-Sanjuan	1995	HS	Dysplasia	HGD rectum	3.5	Pouch
Sequens	1997	Stapled	Carcinoma	CA rectum	1	ATZ
Vieth	1998	HS	Carcinoma	CA colon, multifocal dysplasia	2	Pouch
Iwama	2000	HS	UC	LGD	18	Anastomosis
Rotholtz	2001	Stapled	UC	HGD distal margin	7	ATZ
Heuschen	2001	HS	Dysplasia	CA colon	3	Pouch
Laureti	2002	HS	Carcinoma	CA anastomosis	2	Anastomosis
Hyman	2002	Stapled	Dysplasia	HGD distal margin & colon	5	Rectal stump
Baratsis	2002	Stapled	UC	CA cecum, multifocal dysplasia	2	ATZ
Bentrem	2003	HS	UC	CA colon, dysplasia	14	Pouch
Hassan	2003	HS	UC	UC	2	Pouch
Negi	2003	HS	Dysplasia	HGD	5	Rectal stump
Bell	2003	Stapled	Dysplasia	HGD colon	12	Anastomosis
Lee	2005	HS	Dysplasia	HGD rectum	2	Anastomosis
Lee	2005	HS	Dysplasia	CA rectum	6.5	Anastomosis
Lee	2005	HS	UC	UC	16	Rectal stump
Schaffzin	2005	HS	NR	NR	25	Pouch
Knupper	2006	Stapled	UC	NR	3	Pouch
Walker	2006	HS	NR	Dysplastic colon & rectum	17	Pouch
Das	2007	HS	UC	UC	25	ATZ
Ota	2007	HS	NR	UC	7	Rectal stump
Ruffolo	2007	Stapled	Carcinoma	CA colon at two sites	3	ATZ
Koh	2008	Stapled	NR	NR	14	Pouch inlet
Pedersen	2008	HS	HGD	CA colon, dysplastic colon	11	Rectal stump
Chia	2008	Stapled	UC	CA	3	ATZ

¹Excludes articles not in English and one study using Cavitron Ultrasonic Surgical Aspirator technique for rectal mucosal stripping;

²Yr to presentation of carcinoma after RPC IPAA; HS: Handsewn anastomosis; Stapled: Stapled anastomosis; NR: Not recorded or unknown; UC: Ulcerative colitis, HGD: High grade dysplasia; CA: Carcinoma; LGD: Low grade dysplasia.