Portal hypertensive colopathy is associated with portal hypertension severity in cirrhotic patients

Table 1 Clinical characteristics and hemodynamic data (mean ± SD, n = 88) n (%)

Sex (M/F)	71 (80.7)/17 (19.3)
Etiology
Excessive alcohol consumption	40 (45.5)
HCV	20 (22.7)
HBV	9 (10.2)
HCV and excessive alcohol consumption	8 (9.1)
Other	11 (12.5)
Child-Pugh grade
A	17 (19.3)
B and C	71 (80.7)
Hepatocellular carcinoma	30 (34.1)
Ascites	63 (71.6)
SBP	22 (23.9)
Hepatic encephalopathy	30 (34.1)
Previous variceal bleeding	16 (18.2)
Age (yr)	55 ± 7
Hemoglobin (g/dL)	11.8 ± 2.4
Platelets (cells/μL)	87 443 ± 51 720
Leukocytes (cells/μL)	6286 ± 8932
INR	1.58 ± 0.53
Total bilirubin (mg/dL)	4.2 ± 4.4
Serum albumin (g/dL)	3.2 ± 0.6
α-fetoprotein (ng/mL)	65.1 ± 299.3
CEA (ng/mL)	5.4 ± 10.6
HVPG (mmHg, n = 77)	17.5 ± 5.8

HCV: Hepatitis C virus; HBV: Hepatitis B virus; SBP: Spontaneous bacterial peritonitis; CEA: Carcino-embryonic antigen; HVPG: Hepatic venous pressure gradient.

Table 2 Portal hypertension-related endoscopic variables

	n (%)
Gastroesophageal varices	69 (78.4)
Portal hypertensive gastropathy	40 (48.2)
Portal hypertensive duodenopathy	11 (13.3)
Portal hypertensive colopathy	21 (23.9)
Mild	13 (61.9)
Severe	8 (38.1)
Colonic varices	7 (8)
Internal or mixed hemorrhoids	46 (52.3)

Table 3 Comparison of clinical and endoscopic findings between PHC and non-PHC groups (mean ± SD) n (%)

	PHC group (n = 21)	Non-PHC group (n = 67)
Age (yr)	54.6 ± 7.4	55.2 ± 7
Hemoglobin (g/dL)	11.8 ± 2.6	11.8 ± 2.4
HVPG (mmHg, n = 77)	19.9 ± 6.3	16.8 ± 5.5a
Sex
Male	18 (85.7)	53 (79.1)
Female	3 (14.3)	14 (20.9)
Child-Pugh grade
A	4 (19)	13 (19.4)
B and C	17 (81)	54 (80.6)
Excessive alcohol consumption	13 (61.9)	35 (52.2)
SBP	10 (47.6)	12 (17.9)a
Gastroesophageal varices	19 (90.5)	50 (74.6)
PH gastropathy	11 (55.0)	29 (46.0)
PH duodenopathy	2 (10.0)	9 (14.3)
Adenoma/adenocarcinoma	13 (61.9)	21 (31.3)a

^aP < 0.05 (ANOVA) vs PHC group. PHC: Portal hypertensive colopathy; PH: Portal hypertension.