Usefulness of magnifying endoscopy in post-endoscopic resection scar for early gastric neoplasm: A prospective short-term follow-up endoscopy study

Table 1 Patient characteristics

Parameter
Case (Patient)	129 (124)
Male	79
Female	45
Age, yr (SD)	58.51 (11.27)
Male	59.48 (11.79)
Female	56.71 (10.13)
ER outcome
ESD/EMR	104/25
Complete resection	123
En bloc	117
Piecemeal	6
Incomplete resection	6
Post-ER diagnosis
Adenoma	43 lesions
Adenoma with HGD	48 lesions
Adenocarcinoma	38 lesions
Follow up mo (SD)	2.27 (0.46)

SD: Standard deviation; ER: Endoscopic resection; ESD: Endoscopic submucosal dissection; EMR: Endoscopic mucosal resection; HGD: High grade dysplasia.

Table 2 Endoscopic findings and pit pattern in post-ER scar

CE findings	Pit type (No.)				Total (129)	Pvalue
	I (47)	II (54)	III (19)	IV (9)
Height						0.205
Elevated	14	20	3	6	38
Flat	29	29	13	3	79
Depressed	4	5	3	0	12
Nodularity						0.091
Present	17	18	11	6	53
Absent	30	36	8	3	76
Color						0.079
Erythematous	30	31	16	8	85
Iso or pale	17	23	3	1	44
Ulceration						0.285
Present	0	2	1	1	4
Absent	47	52	18	8	125

CE: Conventional endoscopy; I: Round pit; II: Short rod or tubular pit; III: Branched or gyrus-like pit; IV: Destroyed pit pattern.

Table 3 Endoscopic findings and pathologic result in post-ER scar

CE findings (No.)	Pathologic results
	Non-neoplastic	Neoplastic	Sensitivity (%) (95% CI)	Specificity (%) (95% CI)	PPV (%) (95% CI)	NPV (%) (95% CI)
Presence of nodularity (53)	45	8	88.9 (68.4-100)	62.5 (53.8-71.2)	15.1 (5.5-24.7)	98.7 (96.1-100)
Erythematous lesion (85)	76	9	100.0	36.7 (28.0-45.3)	10.6 (4.0-17.1)	100.0
Presence of ulcer (4)	3	1	11.1 (0.0-31.6)	97.5 (94.7-100)	25.0 (0.0-67.4)	93.6 (89.3-97.9)
Total No.	120	9

PPV: Positive predictive value; NPV: Negative predictive value; CE: Conventional endoscopy.

Table 4 Pit pattern and non-neoplastic pathologic findings (mean score) in post-ER scar

Pit type	Foveolar hyperplasia	Gland congestion	Intestinal metaplasia	Atrophy	Fibrosis
I	0.96	0.64	1.09	1.11	0.21
II	0.96	0.48	1.11	1.11	0.19
III	0.84	0.79	1.05	1.26	0.11
IV (coexisting findings with tumor)	0.78	0.89	1.33	1.56	0.33
P value1	0.837	0.244	0.828	0.34	0.644

Scored from 0 to 3, respectively (0 = normal, 1 = mild, 2 = moderate, 3 = severe). ¹Statistical significances were tested by one-way analysis of variance.

Table 5 Pit pattern and pathologic result in post-ER scar

Pit type	Pathologic results
	Non-neoplastic	Neoplastic
I: Round	47	0
II: Short rod or tubular	54	0
III: Branched or gyrus-like	19	0
IV: Destroyed1	0	9
Total No.	120	9

¹Sensitivity: 100%; Specificity: 100%; Positive predictive value: 100%.