Assessment of the hepatic microvascular changes in liver cirrhosis by perfusion computed tomography

Table 1 Correlations between control subjects and cirrhotic patients on perfusion parameters (mean ± SD)

Parameters	Controls	Cirrhotics	t value	P value
MTT (s)	15.613 ± 3.942	12.212 ± 4.632	3.186	0.002
PS (mL/min per 100 mL)	18.945 ± 7.235	24.964 ± 8.298	-3.121	0.003

Mean transit time (MTT) in cirrhotics was shorter than in the controls (P = 0.002). Permeability surface area product (PS) was higher in cirrhotics than in controls (P = 0.003).

Table 2 Comparison among control subjects and compensated and decompensated cirrhosis patients on perfusion parameters (mean ± SD)

Group	n	MTT (s)	PS (mL/min per 100 mL)
Control	29	15.613 ± 4.175	18.945 ± 7.235
Compensated	22	12.592 ± 4.752	22.767 ± 8.394
Decompensated	17	11.721 ± 4.568	27.806 ± 7.473

MTT: Controls vs compensated, P = 0.059; controls vs decompensated, P = 0.017; compensated vs decompensated, P = 1.000. PS: Controls vs compensated, P = 0.25; controls vs decompensated, P = 0.001; compensated vs decompensated, P = 0.139.