Safety of anti-tumor necrosis factor therapy in inflammatory bowel disease

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May 7, 2009 (publication date) through Nov 11, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. May 7, 2009; 15(17): 2067-2073
Published online May 7, 2009. doi: 10.3748/wjg.15.2067

Table 1 Side effects associated with anti-TNF therapy

Side effect	Example
Infections	Tuberculosis, histoplasmosis
Antibody formation	Antibodies to infliximab, antibodies to adalimumab
Infusion reactions	Anaphylaxis, delayed-type hypersensitivity
Autoimmunity	Antinuclear antibodies
Malignancies	Hepatosplenic T-cell lymphoma
Demyelization	Guillain-Barré syndrome
Abnormal liver function tests	Hepatitis, cholestatic disease
Cardiac abnormalities	Heart failure
Skin eruptions	Psoriasiform dermatitis

Citation: Hoentjen F, van Bodegraven AA. Safety of anti-tumor necrosis factor therapy in inflammatory bowel disease. World J Gastroenterol 2009; 15(17): 2067-2073
URL: https://www.wjgnet.com/1007-9327/full/v15/i17/2067.htm
DOI: https://dx.doi.org/10.3748/wjg.15.2067