Hepatoxicity associated with weight-loss supplements: A case for better post-marketing surveillance

Table 1 Patients, symptoms and laboratory values reported with hydroxycut associated hepatoxicity

Citation	Dara et al[1]		Jones et al[4]	Shim et al[3]	Stevens et al[2]
Patient age (yr)	40	33	19	28	27	30
Patient gender	F	F	M	M	M	M
Reported symptoms/duration	Fatigue, nausea, vomiting, cramping, fever, chills, anorexia/3 d	Fatigue, nausea, cramping, abdominal pain/2 wk	Nausea, vomiting, jaundice/6 d	Fatigue, dyspnea on exertion, jaundice/ 3 wk	Fatigue, jaundice/8 d	Fatigue, vomiting, jaundice, fever/10 d
Aspartate aminotransferase (U/L)	1020	934	1981	1049	1808	59
Alanine aminotransferase (U/L)	1150	570	1143	2272	3131	45
Serum alkaline phosphatase (U/L)	299	112	153	153	171	530
Serum bilirubin (mg/L)	6.7	209	117	181	78	78
Serum direct bilirubin (mg/L)	Not reported	142	68	90	Not reported	Not reported
Prothrombin time (s)	Not reported	Not reported	17.1	12.8	16	15