Almeida AM, Cotrim HP, Barbosa DBV, Athayde LGM, Santos AS, Bitencourt AGV, Freitas LAR, Rios A, Alves E. Fatty liver disease in severe obese patients: Diagnostic value of abdominal ultrasound. World J Gastroenterol 2008; 14(9): 1415-1418 [PMID: 18322958 DOI: 10.3748/wjg.14.1415]
Corresponding Author of This Article
Helma Pinchemel Cotrim, PhD, Faculdade de Medicina da Bahia, Universidade Federal da Bahia, Avenida Tancredo Neves, Ed. Salvador Trade Center, Torre Norte-Sala 717, Salvador, Bahia 41830-020, Brazil. helmacotrim@terra.com.br
Article-Type of This Article
Rapid Communication
Open-Access Policy of This Article
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World J Gastroenterol. Mar 7, 2008; 14(9): 1415-1418 Published online Mar 7, 2008. doi: 10.3748/wjg.14.1415
Table 1 Demographic and clinical characteristics of severe obese patients who underwent to bariatric surgery
Characteristics
Value
Female gender - n (%)
79 (75.2)
Age, in yr - mean ± SD
37.2 ± 10.6
BMI, in kg/m2 - mean ± SD
43.8 ± 5.2
Elevated waist circumference - n (%)
105 (100)
Hypertension - n (%)
55 (52.4)
Diabetes - n (%)
10 (9.5)
Dyslipidemia - n (%)
75 (71.4)
Exposure to chemicals - n (%)
10 (9.5)
Elevated transaminases –n (%)
30 (28.6)
HDL cholesterol - mean ± SD
46.5 ± 5.2
Triglyceride - mean ± SD
157.3 ± 82.8
Fasting plasma glucose level - mean ± SD
102.6 ± 40.8
Insulin resistance - n (%)
52 (49.5)
Table 2 Levels of sensibility, specificity, PPV and NPV for the ultrasound in the diagnosis of hepatic steatosis by body mass index (BMI) values
Variables
35.0 kg/m2 ≤BMI ≤40 kg/m2
BMI≥40 kg/m2
Value (%)
95% CI
Value (%)
95% CI
Sensibility
65
40.9-83.7
64.4
52.2-75.0
Specificity
75
21.9-98.7
100
56.1-100
PPV
92.9
64.2-99.6
100
90.6-100
NPV
30
8.1-64.6
21.2
9.6-39.4
Table 3 Levels of sensibility, specificity, PPV and NPV for the ultrasound in the diagnosis of hepatic steatosis by waist circumference (WC) in severe obese patients
Variables
WC ≤116.9 kg/m2
WC≥117.0 kg/m2
Value (%)
95% CI
Value (%)
95% CI
Sensibility
56.7
37.7-74.0
80
62.5-90.9
Specificity
85.7
42.0-99.2
100
19.8-100
PPV
94.4
70.6-99.7
100
85.0-100
NPV
31.6
13.6-56.5
22.2
3.9-59.8
Table 4 Ultrasound evaluation and grades of steatosis among severe obese patients with steatosis on biopsy (%)
Imaging profile
Grade of steatosis on histological evaluation
Grade I/II
Grade III/IV
Ultrasound without steatosis
97.00
3.00
Ultrasound with steatosis
77.00
23.00
Citation: Almeida AM, Cotrim HP, Barbosa DBV, Athayde LGM, Santos AS, Bitencourt AGV, Freitas LAR, Rios A, Alves E. Fatty liver disease in severe obese patients: Diagnostic value of abdominal ultrasound. World J Gastroenterol 2008; 14(9): 1415-1418