Editorial
Copyright ©2008 The WJG Press and Baishideng.
World J Gastroenterol. Feb 21, 2008; 14(7): 985-990
Published online Feb 21, 2008. doi: 10.3748/wjg.14.985
Table 1 Factors that regulate LES function
Factors that increase tLESRsFactors that decrease tLESRs
Gastric distentionGABA agonists
Pharyngeal stimulationAnticholinergics
High-fat mealsOpioid receptor agonists
CCK-A receptor agonistsNitric oxide synthase inhibitors
Endoscopic therapy
Fundoplication