Ursodeoxycholic acid treatment improves hepatocyte ultrastructure in rat liver fibrosis

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Feb 21, 2008 (publication date) through Nov 21, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Feb 21, 2008; 14(7): 1108-1111
Published online Feb 21, 2008. doi: 10.3748/wjg.14.1108

Table 1 Ultrastructural scoring system

Nucleus
0:	Normal
1:	Irregular chromatin distribution
	-Margination
	-Clumping
2:	Increased heterochromatin
3:	Degenerated nucleus
Mitochondria
0:	Normal
1:	Prominent cristae
2:	Swelling
3:	Collection of amorphous material
RER
0:	Normal
1:	Dilatation
2:	Irregular lamellar organization
3:	Presence of focal breaks
SER
0:	Normal
1:	Dilatation
2:	Presence of vacuole formation (vacuolization)
3:	Presence of focal breaks

Citation: Mas N, Tasci I, Comert B, Ocal R, Mas MR. Ursodeoxycholic acid treatment improves hepatocyte ultrastructure in rat liver fibrosis. World J Gastroenterol 2008; 14(7): 1108-1111
URL: https://www.wjgnet.com/1007-9327/full/v14/i7/1108.htm
DOI: https://dx.doi.org/10.3748/wjg.14.1108