Capsule endoscopy in neoplastic diseases

Table 1 Incidence of small-bowel tumors (modified from Neugut et al[1])

Population/area	Ref.	Time interval	Cases of SB tumor	Incidence per million
Los Angeles County	4	1972-1985	264	-
Nine SEER Registers	5	1973-1982	366	9.6
Cancer register of British Columbia, Alberta, Saskatchewan, Manitoba	6	1975-1989	263	11
Utah Cancer registry	7	1966-1999	442	14
Nine SEER registers	8	1973-1991	892	13
Connecticut Tumor registry	9	1980-2000	1260	8.8

SEER: Surveillance epidemiology and end result.

Table 2 Summary of CE studies for small-bowel tumors

Study[ref]	Population	Tumor cases (%)	Mean age of patients with tumors (yr)	Malignant tumors (%)	Tumors leading to capsule retention (%)
Cobrin et al[28]	562	50 (8.9)	63	48	0
Bailey et al[29]	416	27 (6.3)	61	63	3/26 (11.5)
Urbain et al[31]	443	11 (2.5)	63	100	0
Estevez et al[30]	320	23 (7.8)	63	NA	NA
Schwartz et al[32]	NA	87 (NA)	60	60	NA
Pasha et al[33]	1000	16 (1.6)	67	86	4/16 (25)
Rondonotti et al[34]	5129	124 (2.4)	59	NA	12/124 (9.7)

NA: Not applicable (these data are not reported in the paper).

Table 3 Frequency of capsule retention in patients undergoing capsule endoscopy (modified from Pennazio[50])

Clinical indication	Frequency of capsule retention (%)
Healthy volunteers	0
Obscure GI bleeding	1.5
Suspected Crohn’s disease	1.4
Known Crohn’s disease	4-13
Small-bowel tumor	10-25
Suspected small-bowel obstruction	21