Resting energy expenditure and glucose, protein and fat oxidation in severe chronic virus hepatitis B patients

Table 1 Clinical characteristics of the patients

Group	n	Age (yr)	Male/Female	ALT (U/L)	AST (U/L)	T-Bil (mg/dL)	ALB (g/L)	PA (g/L)	CHE (g/L)	CH (g/L)
1	16	34 ± 16	10/6	154.3 ± 184.8	68.3 ± 58.4	4.4 ± 6.4	36.6 ± 4.4	142.0 ± 66.0	6050.9 ± 2243.6	164.9 ± 49.4
2	56	46 ± 13	49/9	189.2 ± 374.9	156.8 ± 159.4	20.4 ± 9.8	29.8 ± 4.6	52.5 ± 27.5	2723.6 ± 1422.2	52.3 ± 36.2
3	28	53 ± 10	24/4	68.3 ± 118.9	80.2 ± 80.6	5.8 ± 7.2	29.5 ± 7.2	62.2 ± 34	2628.6 ± 1416.3	114.9 ± 42.7

Group 1: Acute hepatitis group; Group 2: Chronic severe hepatitis group; Group 3: Cirrhosis group. PTA: Prothrombin activity. PTA = (control PT-8.7)/(patients PT-8.7) × 100%.

Table 2 REE and oxidation rates in different groups of patients with liver disease (mean ± SD)

Group	REE (kcal/d)	REE/kg (kcal/d)	RQ	npRQ	CHO (g/d per kg)	Fat (g/d per kg)	Protein (g/d per kg)
1	1586.7 ± 783.0	25.8 ± 11.3	0.90 ± 0.05	0.92 ± 0.21	3.8 ± 2.1	0.5 ± 0.5	1.1 ± 0.6
2	1388.5 ± 334.5	20.7 ± 6.1	0.84 ± 0.06a	0.88 ± 0.18	1.8 ± 1.0a	0.9 ± 0.7	0.9 ± 0.6
3	1317.9 ± 266.3	19.8 ± 3.6	0.88 ± 0.08	0.91 ± 0.09	2.7 ± 1.4	0.9 ± 2.0	1.0 ± 0.6
P value	0.126	0.014	0.001	0.441	0	0.721	0.525

Group 1: Acute hepatitis group; Group 2: Chronic severe hepatitis group; Group 3: Cirrhosis group.

^aP < 0.05, 2 vs 1 and 3 vs 1.

Table 3 Dynamic determination of REE and oxidation rates in severe chronic hepatitis patients (n = 14, mean ± SD)

Patient	REE (kcal/d)	REE/kg (kcal/d per kg)	RQ	CHO (%)	Fat (%)	Protein (%)
Severe stage	1366.1 ± 140.7	19.1 ± 3.3	0.86 ± 0.05	41.7 ± 18.3	26.3 ± 27.2	32.1 ± 24.8
Recovery stage	1306.7 ± 497.8	17.9 ± 6.2	0.91 ± 0.06	60.1 ± 11.7	7.6 ± 38.6	32.3 ± 30.9
P value	0.761	0.638	0.105	0.075	0.232	0.990