Staging of portal hypertension and portosystemic shunts using dynamic nuclear medicine investigations

Table 1 Features of the study population according to the final diagnosis (n)

Type of disease	Number of patients
Steatosis	17
Chronic hepatitis	69
Cirrhosis	202
Unknown	3
CLD infirmed	21
Total	312

Table 2 Etiology for the patients with chronic liver disease (n)

Etiology	Number of patients
Viral	139
Alcohol	74
Mix (viral + alcohol)	6
Unknown	72
Total	291

Table 3 Distribution of all the patients and of those with cirrhosis according to the per-rectal portal shunt index and to our classification in 5 stages

Per-rectal portal shunt index (%)	Number of patients (n)		Cirrhosis	Stage in our classification
0-5	65		0	Stages 0 & 1
5-10	13		5	Stage 2
10-20	42	80	43	Stage 3
20-30	38
30-40	17	154	154	Stage 4
40-50	10
50-60	11
60-70	10
70-80	18
80-90	40
90-100	48
Total	312		202

Table 4 Statistical analysis of the per-rectal portal shunt index for healthy subjects and for the different stages of chronic liver disease using Kruskall-Wallis test

Disease	Number of patients (n)	Sum of ranks
CLD infirmed	21	759.5
Steatosis	17	1201.5
Chronic hepatitis	69	5004.5
Cirrhosis	202	40929.5

Kruskall-Wallis test: H (3, n = 309) = 169.5024, P = 0.000.

Table 5 Liver transit time and distribution in stages of the patients with the per-rectal portal shunt index lower than 10%

Per-rectal shunt index	Mean value of liver transit time (s)		Etiology	Number of patients (n)	Stage in our classification
	Right lob	Left lobe
< 5%	24		-	38	Stage 0
	25	28	viral	10	Stage 1a
	31	24	alcoholic	6	Stage 1b
	31.5	29	viral	7	Stage 1c
			viral + alcoholic	4
5%-10%	19.5			13	Stage 2