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©2008 The WJG Press and Baishideng.
World J Gastroenterol. Jun 14, 2008; 14(22): 3526-3533
Published online Jun 14, 2008. doi: 10.3748/wjg.14.3526
Published online Jun 14, 2008. doi: 10.3748/wjg.14.3526
Table 1 Baseline characteristics of 48 patients with HCC
| Characteristics | |
| Mean age (yr) | 50 (20-71) |
| Sex (M:F) | 35:13 |
| Etiology of liver disease | |
| HBV | 38 |
| HCV | 3 |
| Non-HBV, Non-HCV | 7 |
| Tumor size | |
| ≤ 3 cm | 11 |
| 3-5 cm | 15 |
| > 5 cm | 22 |
| Mean ( range) (cm) | 5.8 ± 3.9 |
| UICC TNM stage | |
| I | 5 |
| II | 41 |
| III | 2 |
| Edmonson-Steiner’s grade | |
| I | 8 |
| II | 13 |
| III | 20 |
| IV | 5 |
| Underlying liver disease | |
| Cirrhosis | 22 |
| Chronic hepatitis | 26 |
| AFP (ng/mL) | |
| < 11 | 12 |
| 11-400 | 16 |
| ≥ 400 | 20 |
Table 2 p53 mutation analysis in 48 patients with HCC
| Mutation sites | n | Mutation sites | n |
| Exon 5 | Exon 8 | ||
| Arg(CGC)158Leu(CTC) | 1 | Arg(CGT)273Cys(TGT) | 1 |
| Exon 6 | Exon 7 | ||
| His(CAT)193Tyr(TAT) | 1 | Arg(TAC)236Cys(TGC) | 1 |
| Ser(AGT)215Arg(AGG) | 1 | Arg(TAC)236Asp(GAC) | 1 |
| Tyr(TAT)220Cys(TGT) | 1 | Met(ATG)246Leu(TTG) | 1 |
| Met(ATG)246Val(GTG) | 1 |
- Citation: Nam CW, Shin JW, Park NH. Fragile histidine triad gene alterations are not essential for hepatocellular carcinoma development in South Korea. World J Gastroenterol 2008; 14(22): 3526-3533
- URL: https://www.wjgnet.com/1007-9327/full/v14/i22/3526.htm
- DOI: https://dx.doi.org/10.3748/wjg.14.3526